Langer-Giedion syndrome is a very rare genetic disorder caused by a deletion of chromosomal material. It is named after the two doctors who undertook the main research into the condition in the 1960s. Diagnosis is usually made at birth or in early childhood.

The syndrome occurs when a small piece of chromosome 8’s long arm, which contains a number of genes is missing. The loss of these genes is responsible for some of the overall characteristics of Langer-Giedion syndrome. This disorder is also called trichorhinophalangeal syndrome, or LGCR (for Langer-Giedion Chromosome Region).

Symptoms

---

The features associated with this condition include mild to moderate learning difficulties, short stature, unique facial features, small head and skeletal abnormalities including bony growths projecting from the surfaces of bones. These may include benign bony growths on various bones of the body or cone-shaped extensions on the growing ends of certain bones, particularly in the hands, and specific craniofacial features. Typically individuals with Langer-Giedion syndrome have fine scalp hair, ears, which may be large, or prominent, broad eyebrows, deep-set eyes, a bulbous nose, long narrow upper lip and missing teeth.

More on [ Langer-Giedion syndrome ]

NYT > Health

Patient Money: For a Frugal Dieter, Weight Loss on a Sliding Scale
By LESLEY ALDERMAN Sat, 04 Jul 2009 05:42:07 -0000
A dieter’s commitment to weight loss can sometimes be linked to how much money he or she is willing to spend.
Global Update: Tuberculosis: TB Vaccine Too Dangerous for Babies With AIDS Virus, Study Says
By DONALD G. McNEIL Jr. Sat, 04 Jul 2009 04:40:26 -0000
A common tuberculosis vaccine is too risky to give to those born infected with the AIDS virus, says a new study published by the World Health Organization.
Swine Flu Death Toll in Argentina Climbs
By ALEXEI BARRIONUEVO Sat, 04 Jul 2009 06:15:21 -0000
Argentina’s president said she would not rule out closing major public venues where swine flu could spread more quickly.

CNN.com - Health

Police: Hospital worker swiped shots, spread hep C
Fri, 03 Jul 2009 18:18:42 -0400
A former hospital employee may have exposed hundreds or thousands of surgical patients to hepatitis C when she replaced clean needles filled with the powerful painkiller fentanyl with her own dirty needles filled with saline solution.
Health.com picks top beach, lake getaways
Fri, 03 Jul 2009 13:47:40 -0400
We know your summer vacation time is precious: You want to land where you can truly relax, breathe fresh air, get in some exercise and eat well -- without breaking the bank. That's why we teamed up with a panel of travel and health experts to help us find the healthiest of the nation's most popular beach and lake towns.
Suit: Toxic plane air sickens flight attendant
Fri, 03 Jul 2009 13:31:03 -0400
The last time Terry Williams can remember being headache-free was in December. A chronic migraine has plagued her ever since. So have balance and vision problems, a tremor in her left arm, a prickly sensation in her feet and a loss of childhood memories.

BBC News | Health | World Edition

Self-help 'makes you feel worse'
Fri, 03 Jul 2009 23:06:55 -0000
Bridget Jones is not alone in turning to self-help mantras to boost her spirits, but a study warns they may have the opposite effect.
WHO warns swine flu 'unstoppable'
Fri, 03 Jul 2009 03:00:11 -0000
The UN's top health official tells a swine flu forum in Mexico that the spread of the virus worldwide is now unstoppable.
Solo life ups gene dementia risk
Thu, 02 Jul 2009 23:25:24 -0000
People who have a gene flaw and live alone in middle-age are at highest risk of developing dementia, a study suggests.

Subscribe to Support_Groups RSS feed