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An allergy can refer to several kinds of immune reactions including Type I hypersensitivity in which a person's body is hypersensitised and develops IgE type antibodies to typical proteins. When a person is hypersensitised, these substances are known as allergens. The word allergy derives from the Greek words allos meaning "other" and ergon meaning "work". Type I hypersensitivity is characterised by excessive activation of mast cells and basophils by immunoglobulin E resulting in a systemic inflammatory response that can result in symptoms as benign as a runny nose, to life-threatening anaphylactic shock and death.

Allergy is a very common disorder and more than 50 million Americans suffer from allergic diseases. Allergies are the 6th leading cause of chronic disease in the United States, costing the health care system $18 billion annually (Allergy statistics).

History


The term and concept of "allergy" was coined by a Viennese pediatrician named Clemens von Pirquet in 1906 *. He observed that the symptoms of some of his patients might have been a response to outside allergens such as dust, pollen, or certain foods. For a long time all hypersensitivities were thought to stem from the improper action of inflammatory immunoglobulin class IgE, however it soon became clear that several different mechanisms utilizing different effector molecules were responsible for the myriad of disorders previously classified as "allergies". A new four-class (now five) classification scheme was designed by P. G. H. Gell and R. R. A. Coombs. Allergy has since been kept as the name for Type I Hypersensitivity, characterised by classical IgE mediation of effects.

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New post: Enjoy Your Dog With Fewer Allergic Reactions (http://cli.gs/NYGtm) http://cli.gs/NYGtm
WeLoveProject (Simon Lau) Mon, 04 Jan 2010 02:57:27 -0000
New post: Enjoy Your Dog With Fewer Allergic Reactions (http://cli.gs/NYGtm) http://cli.gs/NYGtm
@Tefisheep I thought it was the eggs in it but just found an article saying in 20% of people it can cause severe allergic reactions :/
LauraHickman (Laura Hickman) Mon, 04 Jan 2010 02:40:37 -0000
@Tefisheep I thought it was the eggs in it but just found an article saying in 20% of people it can cause severe allergic reactions :/
DUE TO POSSIBLE ALLERGIC REACTIONS PLEASE DO NOT REMOVE PEANUTS FROM STORE
economyfilms (Jeff Economy) Mon, 04 Jan 2010 01:26:22 -0000
DUE TO POSSIBLE ALLERGIC REACTIONS PLEASE DO NOT REMOVE PEANUTS FROM STORE
Updated my blog with Allergic Reactions Symptoms http://bit.ly/65zgpi
wernermheus (Werner Michael Heus) Mon, 04 Jan 2010 00:30:44 -0000
Updated my blog with Allergic Reactions Symptoms http://bit.ly/65zgpi
Pet Allergy - Allergic Reactions to Dog and Cat Hair | Healthy Kiwi: Pet allergies due to animal dander … dog hai... http://bit.ly/5yNgNw
vmadyson (Fantine Madyson) Mon, 04 Jan 2010 00:00:47 -0000
Pet Allergy - Allergic Reactions to Dog and Cat Hair | Healthy Kiwi: Pet allergies due to animal dander … dog hai... http://bit.ly/5yNgNw
allergic reactions suck. :|
mikaeellaaa (mikkaaaeeellalalalaa) Sun, 03 Jan 2010 23:26:35 -0000
allergic reactions suck. :|

 
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