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Zoledronate (INN: zoledronic acid, marketed by Novartis under the trade name Zometa®) is a bisphosphonate, used to prevent osteoporosis and skeletal fractures, particularly in patients with cancers such as multiple myeloma and prostate cancer. It can also be used to treat hypercalcemia, particularly hypercalcemia of malignancy. It can also be helpful for treating pain from bone metastases.

Administration


Usually 4 mg intravenously once a month when given for oncologic purposes. It is given once a year for treatment of osteoporosis.

Side effects


Side effects can include fatigue, anemia, muscle aches, fevers, and swelling in the feet or legs. Zoledronate can cause deterioration in renal function.

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DrugDigest: Zoledronic Acid Injection ( Zometa ) - Information on dosage, usage, side effects, and interactions.

Zometa - Features product information for US residents healthcare professionals, including safety information and reimbursement details.
Meta Description: [ How Zometa (zoledronic acid) injection works: cancer and your bones, breast cancer, lung cancer, prostate cancer, multiple myeloma, bone health. Zometa may reduce or delay bone complications. ]

Zometa International - A web-site created to inform healthcare providers outside the US
Meta Description: [ Zometa.com is a website created by Novartis Pharma to inform healthcare professionals outside the US on the drug Zometa (zoledronic acid), which is indicated for the prevention of skeletal related events in patients with advanced malignancies involving bone. These malignancies include multiple m... ]

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