Zaleplon (marketed under the brand names Sonata® and Starnoc®) is a sedative/hypnotic, mainly used for insomnia. It is a nonbenzodiazepine hypnotic from the pyrazolopyrimidine class.

Chemistry

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Zaleplon is a white to off-white powder that has very low solubility in water as well as low solubility in alcohol and propylene glycol. It has a partition coefficient in octanol/water is constant (log PC = 1.23) when the pH range is between 1 and 7.

Mode of action

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Taken orally, Zaleplon reaches full concentration in approximately one hour. It is extensively metabolised, into 5-oxo-zaleplon and 5-oxo-desethylzaleplon (the latter via desethylzaleplon), with less than 1% of it excreted intact in urine.

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ManuraNanayakka (Manura Nanayakkara) Sun, 08 Jan 2012 23:25:13 -0000
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njnuwantha (Dr Nuwan Nanayakkara) Sun, 08 Jan 2012 16:19:21 -0000
Side effects of Zaleplon http://t.co/KorkKWmI
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ManuraNanayakka (Manura Nanayakkara) Sun, 08 Jan 2012 15:32:20 -0000
A good drug to induce #sleep, #insomnia Zaleplon http://t.co/6j1yW9ki
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