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Warfarin (also known under the brand names of Coumadin®, Jantoven®, Marevan®, and Waran®) is an anticoagulant medication that is administered orally or, very rarely, by injection. It is used for the prophylaxis of thrombosis and embolism in many disorders. Its activity has to be monitored by frequent blood testing for the international normalized ratio (INR). It is named for the Wisconsin Alumni Research Foundation.

Warfarin was originally developed as a rat poison, and is still widely used as such, although warfarin-resistant rats are becoming more common.

Mechanism of action


Warfarin inhibits the effective synthesis of biologically active forms of the vitamin K-dependent clotting factors: II, VII, IX and X, as well as the regulatory factors protein C, protein S and protein Z. Other proteins not involved in blood clotting, such as osteocalcin, may also be affected.

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Blood Coagulation Disorders
Thrombosis :: Vascular Disorders

 
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Coumadin versus warfarin
ijvsewqz (Carreen Licence) Fri, 10 Feb 2012 05:29:36 -0000
Coumadin versus warfarin
Prediction of Warfarin Dose Reductions in Puerto Rican Patients, Based on Combinatorial CYP2C9 and VKORC1 Genotypes http://t.co/IEDPpjBW
Life_Sciences_ (Life Sciences) Fri, 10 Feb 2012 04:46:10 -0000
Prediction of Warfarin Dose Reductions in Puerto Rican Patients, Based on Combinatorial CYP2C9 and VKORC1 Genotypes http://t.co/IEDPpjBW
Foods that interact with Coumadin, Warfarin http://t.co/GbRF8iWA
PSedesseMD (Peter Sedesse MD) Fri, 10 Feb 2012 04:45:10 -0000
Foods that interact with Coumadin, Warfarin http://t.co/GbRF8iWA
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Coumadin - Product information, patient education, clinical data, helpful links and services are available for patients and healthcare professionals for warfarin sodium.

DrugDigest: Warfarin - Information on dosage, usage, side effects, interactions, and drug comparisons including generics when available.

Jantoven - Upsher Smith - Official pharmaceutical website with a patient information section and a section for health professionals.
Meta Description: [ JANTOVEN.com provides information and resources to help patients and caregivers start and maintain safe, effective anticoagulation with JANTOVEN. ]

404 MSNBC News: Warfarin, Cranberry Juice Warning - Warns of a potentially fatal interaction between the drug and beverage.
Meta Description: [ Our web servers cannot find the page or file you asked for.The link you followed may be broken or expired. ]

Warfarinfo.com - Information about the drug including its history, food and drug interactions, and FAQs.
Meta Description: [ The home page of the Warfarin Institute of America. Dedicated to helping people who take warfarin live healthy lives. ]

Warfarininfo.com - Sponsored by Barr Laboratories, Inc. and provides patients and health care professionals with information and educational materials.
Meta Description: [ Welcome to www.warfarininfo.com, an important resource for anticoagulation therapy information. This site is sponsored by Barr Laboratories, Inc. and provides patients and health care professionals with important information and educational materials about Warfarin Sodium Tablets, USP. ]

Warfarissimo - A free-to-use web interface that will simulate the action of oral anticoagulants such as warfarin and acenocoumarol based on input scenarios.
Meta Description: [ An on-line simulator of the pharmacokinetics and action of warfarin and acenocoumarol ]

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