Vinorelbine (Navelbine®) is a chemotherapy drug that is given as a treatment for some types of cancer, including breast cancer and non-small-cell lung cancer.

Pharmacology

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Vinorelbine is a vinca alkaloid. It is obtained by semi-synthesis from alkaloids extracted from the rosy periwinkle, Catharanthus roseus.

History

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Vinorelbine was invented in the 1980s by scientists at the pharmaceutical arm of the Pierre Fabre Group. The drug was approved in France in 1989 under the brand name Navelbine for the treatment of bronchial cancer. It gained approval to treat non-small cell lung cancer in 1991. The drug is now primarily used to treat this cancer. Vinorelbine received FDA approval in December 1994 sponsored by GlaxoSmithKline. The drug went generic in the US in February 2003.

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Heme/Onc: Fluorouracil, epirubicin, and cyclophosphamide with either docetaxel or vinorelbine, with or without trastuzum http://url4.eu/hNxB
MDLinx (Sandeep Pulim MD) Thu, 05 Nov 2009 12:23:57 -0000
Heme/Onc: Fluorouracil, epirubicin, and cyclophosphamide with either docetaxel or vinorelbine, with or without trastuzum http://url4.eu/hNxB
A Trial of Gemcitabine Combined With Vinorelbine as First Line Chemotherapy for Metastatic Breast Cancer http://bit.ly/2aam9S
trialscentral (Trials Central) Tue, 03 Nov 2009 18:27:24 -0000
A Trial of Gemcitabine Combined With Vinorelbine as First Line Chemotherapy for Metastatic Breast Cancer http://bit.ly/2aam9S
Study With Vinorelbine and Gemcitabine Versus Capecitabine in Pretreated Metastatic Breast Cancer http://bit.ly/2sVEou
trialscentral (Trials Central) Tue, 03 Nov 2009 18:11:46 -0000
Study With Vinorelbine and Gemcitabine Versus Capecitabine in Pretreated Metastatic Breast Cancer http://bit.ly/2sVEou

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