Vinorelbine (Navelbine®) is a chemotherapy drug that is given as a treatment for some types of cancer, including breast cancer and non-small-cell lung cancer.

Pharmacology

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Vinorelbine is a vinca alkaloid. It is obtained by semi-synthesis from alkaloids extracted from the rosy periwinkle, Catharanthus roseus.

History

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Vinorelbine was invented in the 1980s by scientists at the pharmaceutical arm of the Pierre Fabre Group. The drug was approved in France in 1989 under the brand name Navelbine for the treatment of bronchial cancer. It gained approval to treat non-small cell lung cancer in 1991. The drug is now primarily used to treat this cancer. Vinorelbine received FDA approval in December 1994 sponsored by GlaxoSmithKline. The drug went generic in the US in February 2003.

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Vinorelbine - Twitter Search

lapatinib + vinorelbine in erbb2 overexpressing, 1st or 2nd line metastatic breast cancer ppl http://bit.ly/8bajrl
goclinicaltrial (Clinical Trials) Sat, 19 Dec 2009 00:46:44 -0000
lapatinib + vinorelbine in erbb2 overexpressing, 1st or 2nd line metastatic breast cancer ppl http://bit.ly/8bajrl
lapatinib + vinorelbine in erbb2 overexpressing, 1st or 2nd line metastatic breast cancer ppl http://bit.ly/8bajrl
newtrials_ (New Clinical Trials) Sat, 19 Dec 2009 00:30:47 -0000
lapatinib + vinorelbine in erbb2 overexpressing, 1st or 2nd line metastatic breast cancer ppl http://bit.ly/8bajrl
capecitabine, cyclophosphamide, doxorubicin, gemcitabine, lapatinib, paclitaxel, trastuzumab, or vinorelbine in http://bit.ly/5Ggdmk
usclinicaltrial (US Clinical Trials) Fri, 18 Dec 2009 17:58:53 -0000
capecitabine, cyclophosphamide, doxorubicin, gemcitabine, lapatinib, paclitaxel, trastuzumab, or vinorelbine in http://bit.ly/5Ggdmk
stdy evaluating hki-272 in combo w/ vinorelbine in ppl w/ solid tumors & metastatic breast cancer http://bit.ly/87p9w7
ustrials (US Trials) Thu, 17 Dec 2009 23:34:45 -0000
stdy evaluating hki-272 in combo w/ vinorelbine in ppl w/ solid tumors & metastatic breast cancer http://bit.ly/87p9w7
bvacizumab in combo w/ vinorelbine & trastuzumab 4 her2-positive, metastatic breast cancer http://bit.ly/6n2Piq
usclinicaltrial (US Clinical Trials) Thu, 17 Dec 2009 22:10:46 -0000
bvacizumab in combo w/ vinorelbine & trastuzumab 4 her2-positive, metastatic breast cancer http://bit.ly/6n2Piq
New chemo (Vinorelbine) starting Wed. Last in locker. May get hospital transport home & help upstairs, if can get timing synchronized.
Mezzyp (Mez) Tue, 15 Dec 2009 20:36:22 -0000
New chemo (Vinorelbine) starting Wed. Last in locker. May get hospital transport home & help upstairs, if can get timing synchronized.

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