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Vinblastine is a drug used to treat certain kinds of cancer, including Hodgkin's lymphoma, non-small cell lung cancer and breast cancer or testicular cancer.
It is a chemical analogue of Vincristine (Vinca Alkaloids). It binds tubulin and there by inhibiting the assembly of microtubles. It is G1-S phase cell cycle specific. Toxicities include myelosupression (dose limiting), GI toxicity, a potent vesicant (blister forming), and extravation injury (forms deep ulcers).
It was first discovered by Robert Noble and Charles Thomas Beer from examining the Madagascar periwinkle plant. Vinblastine was first discovered as a useful drug when it was crushed into a tea. The person who drank it had fewer white blood cells. Now, vinblastine is used to lessen immature white blood cells in a patient.
More on [ Vinblastine ]
Hello all, just wanted to tell everyone, my son is going thru chemo. he's on vinblastine just started last week
davery76 (David Thomson) Sat, 07 Nov 2009 13:55:42 -0000
Hello all, just wanted to tell everyone, my son is going thru chemo. he's on vinblastine just started last week
Arts op visite: vincristine wordt vinblastine vw minder bijwerking op darmen; nieren werken goed dus voorlopig geen extra vocht via infuus
heeralewijn (alewijn brouwer) Tue, 03 Nov 2009 10:32:17 -0000
Arts op visite: vincristine wordt vinblastine vw minder bijwerking op darmen; nieren werken goed dus voorlopig geen extra vocht via infuus
Vinblastine (Velban, Velsar) - Dosage, side effects, and other topics, with particular reference to the use of this medication in treating Kaposi's sarcoma.
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