Gourt > Health > Pharmacy > Drugs and Medications > V > Vinblastine
Vinblastine is a drug used to treat certain kinds of cancer, including Hodgkin's lymphoma, non-small cell lung cancer and breast cancer or testicular cancer.
It is a chemical analogue of Vincristine (Vinca Alkaloids). It binds tubulin and there by inhibiting the assembly of microtubles. It is G1-S phase cell cycle specific. Toxicities include myelosupression (dose limiting), GI toxicity, a potent vesicant (blister forming), and extravation injury (forms deep ulcers).
It was first discovered by Robert Noble and Charles Thomas Beer from examining the Madagascar periwinkle plant. Vinblastine was first discovered as a useful drug when it was crushed into a tea. The person who drank it had fewer white blood cells. Now, vinblastine is used to lessen immature white blood cells in a patient.
More on [ Vinblastine ]
genetic vari8s of response 2 cisplatin, vinblastine, & temozolomide in ppl w/ metastatic melanoma http://bit.ly/5GQZIR
paidtrials (US Clinical Trials) Tue, 08 Dec 2009 05:27:41 -0000
genetic vari8s of response 2 cisplatin, vinblastine, & temozolomide in ppl w/ metastatic melanoma http://bit.ly/5GQZIR
genetic vari8s of response 2 cisplatin, vinblastine, & temozolomide in ppl w/ metastatic melanoma http://bit.ly/5GQZIR
localtrials (US Clinical Trials ) Fri, 04 Dec 2009 09:46:39 -0000
genetic vari8s of response 2 cisplatin, vinblastine, & temozolomide in ppl w/ metastatic melanoma http://bit.ly/5GQZIR
neoadjuvant chemothrpy w/ methotrex8, vinblastine, adriamycin & cisplatin + avastin in ppl w/ urothelial cancer http://bit.ly/4JSGKw
houstontrials (houston trials) Thu, 03 Dec 2009 12:08:27 -0000
neoadjuvant chemothrpy w/ methotrex8, vinblastine, adriamycin & cisplatin + avastin in ppl w/ urothelial cancer http://bit.ly/4JSGKw
Abstract: Metronomic Cyclophosphamide and Vinblastine in Refractory Lymphoma http://tinyurl.com/ykgtdlo
CIGMediaGroup (CIG Media Group) Wed, 02 Dec 2009 23:20:45 -0000
Abstract: Metronomic Cyclophosphamide and Vinblastine in Refractory Lymphoma http://tinyurl.com/ykgtdlo
Vinblastine (Velban, Velsar) - Dosage, side effects, and other topics, with particular reference to the use of this medication in treating Kaposi's sarcoma.
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