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Ursodiol
Chemical name Ursodeoxycholic acid
Chemical formula C24H40O4
Molecular mass 392.56 g/mol
CAS number 128-13-2
Melting point 203–206 °C
Ursodiol (trade names Actigall, Ursofalk, Urso, Urso Forte) is a bile acid found in large quantities in bear bile; it also occurs naturally in human bile in smaller quantities.

The drug reduces cholesterol absorption and is used to dissolve gallstones in patients who want an alternative to surgery. The drug is very expensive, however, and if the patient stops taking it, the gallstones recur. For these reasons, it has not supplanted surgical treatment by cholecystectomy. It is also the recommended treatment for Primary biliary cirrhosis, and other cholestatic diseases, and the primary medicine given to children with biliary atresia.

Mechanism of action


Ursodiol, whose chemical name is ursodeoxycholic acid, reduces elevated liver enzyme levels by facilitating bile flow through the liver and protecting liver cells.

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Ursodiol - Familydoctor.org - Information for patients in English and Spanish.

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