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Trovafloxacin (sold as Trovan® by Pfizer) is a broad spectrum antibiotic that inhibits DNA supercoiling in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV *. It is not used widely due to the risk of hepatotoxicity. It tends to have better gram-positive bacterial coverage and less gram-negative coverage than the previous fluoroquinolones.
More on [ Trovafloxacin ]
Antibiotics :: Drugs and Medications
Trovafloxacin - Familydoctor.org - Information for patients in English and Spanish.
Trovan Rx Now Comes With Serious Caveats - News article reporting that US FDA advises using the potent antibiotic only in emergencies because of risks to the liver. From Time.com.
Meta Description: [ FDA advises using the potent antibiotic only in emergencies because of risks to the liver ]
