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Tranylcypromine (sold under the brand name Parnate®) is a monoamine oxidase inhibitor (MAOI) used as an antidepressant drug.

Pharmacology


Tranylcypromine is a non-hydrazine, irreversible monoamine oxidase inhibitor, and has a rapid onset of action.

The antidepressant activity of tranylcypromine is thought to be due to the fact that it increases the concentration of epinephrine, norepinephrine, and serotonin throughout the nervous system. This is achieved through the inhibition of monoamine oxidase.

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