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Tobramycin sulfate is an aminoglycoside antibiotic used to treat various types of bacterial infections, particularly Gram-negative infections.

Mechanism of action


Tobramycin works by binding to a site on the bacterial ribosome, causing the genetic code to be misread.

Administration


Like all aminoglycosides, tobramycin does not pass the gastro-intestinal tract, so for systemic use it can only be given intravenously or intramuscularly. This formulation for injection is branded Nebcin®. Patients with cystic fibrosis will often take an inhalational form (Tobi®) for suppression of Pseudomonas aeruginosa infections. Tobramycin is also combined with dexamethasone as an ophthalmic solution (TobraDex®).

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TOBI (Tobramycin) US: Seattle Children’s Hosp files patent infringemt complaint against Teva in response to its Para IV http://bit.ly/92yoE6
IPThinkTank (DuncanBucknell) Fri, 25 Dec 2009 20:01:33 -0000
TOBI (Tobramycin) US: Seattle Children’s Hosp files patent infringemt complaint against Teva in response to its Para IV http://bit.ly/92yoE6
Service Buyer needs purchase of Marketing authorizations / EU CTD dossiers for Ondansetron & Tobramycin: http://tinyurl.com/yagwjbj
pharmatching (Henriette Fraedrich) Fri, 25 Dec 2009 13:21:23 -0000
Service Buyer needs purchase of Marketing authorizations / EU CTD dossiers for Ondansetron & Tobramycin: http://tinyurl.com/yagwjbj
@Muerten @norasake lol I'm just like it's 5ml what is in it unicorn tears? Lol yes it's working. It's tobramycin and dexamethasone (c)
Wemnar (JJ Valentine) Thu, 24 Dec 2009 16:13:57 -0000
@Muerten @norasake lol I'm just like it's 5ml what is in it unicorn tears? Lol yes it's working. It's tobramycin and dexamethasone (c)
Less than 2 hrs sleep last night,long drive and now late night to do last dose of ivs; will do tobramycin mornings so less time taken in day
skyehighmileage (Sandy Leahy) Thu, 17 Dec 2009 21:33:53 -0000
Less than 2 hrs sleep last night,long drive and now late night to do last dose of ivs; will do tobramycin mornings so less time taken in day

 
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