Terbinafine hydrochloride (Lamisil® in UK & US) is a synthetic allylamine antifungal. It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues.

Pharmacology

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Terbinafine hydrochloride is a white fine crystalline powder that is freely soluble in methanol and methylene chloride, soluble in ethanol, and slightly soluble in water.

Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase -- an enzyme that is part of the fungal sterol synthesis pathway that creates the sterols needed for the fungal cell membrane. In layman's terms, it inhibits fungal and bacterial cell wall growth, causing the contents of the cell to be unprotected and eventually die.

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Steriod medicine. SMZ/TMP medicine. Terbinafine cream. Then bed.
StellarSarah (Sarah Keith) Sun, 08 Nov 2009 04:12:05 -0000
Steriod medicine. SMZ/TMP medicine. Terbinafine cream. Then bed.
Safety and efficacy of terbinafine in a pediatric iranian cohort of patients with tinea capitis http://kele.es/iB6
Sciencia (Webmaster Sciencia) Fri, 06 Nov 2009 07:30:52 -0000
Safety and efficacy of terbinafine in a pediatric iranian cohort of patients with tinea capitis http://kele.es/iB6
Safety and efficacy of terbinafine in a pediatric iranian cohort of patients with tinea ca.. http://bit.ly/31uAYt http://sciencia.org/
Sciencia (Webmaster Sciencia) Fri, 06 Nov 2009 07:10:09 -0000
Safety and efficacy of terbinafine in a pediatric iranian cohort of patients with tinea ca.. http://bit.ly/31uAYt http://sciencia.org/
I/D Terbinafine: a pharmacological and clinical review: Expert Opinion in Pharmacotherapy http://bit.ly/BL4Qk
MDLinx (Sandeep Pulim MD) Tue, 03 Nov 2009 15:29:48 -0000
I/D Terbinafine: a pharmacological and clinical review: Expert Opinion in Pharmacotherapy http://bit.ly/BL4Qk

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