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Terbinafine hydrochloride (Lamisil® in UK & US) is a synthetic allylamine antifungal. It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues.

Pharmacology


Terbinafine hydrochloride is a white fine crystalline powder that is freely soluble in methanol and methylene chloride, soluble in ethanol, and slightly soluble in water.

Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase -- an enzyme that is part of the fungal sterol synthesis pathway that creates the sterols needed for the fungal cell membrane. In layman's terms, it inhibits fungal and bacterial cell wall growth, causing the contents of the cell to be unprotected and eventually die.

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Interactions of Terbinafine Hydrochloride, Adderall 20 for a male aged 29 who has ADHD by eHealthMe http://bit.ly/88i4r0
drugsideeffects (drug side effects) Wed, 23 Dec 2009 22:39:17 -0000
Interactions of Terbinafine Hydrochloride, Adderall 20 for a male aged 29 who has ADHD by eHealthMe http://bit.ly/88i4r0
Iontophoretic terbinafine delivery in onychomycosis: questionable nail growth http://kele.es/p39
Sciencia (Webmaster Sciencia) Tue, 22 Dec 2009 16:37:10 -0000
Iontophoretic terbinafine delivery in onychomycosis: questionable nail growth http://kele.es/p39
Scholl Advance Athlete's Foot Cream 15g | Wart Removal: NEW.Terbinafine Hydrochloride 1% w/w.RELIEVES THE ITCH... http://bit.ly/5hu1lD
pertsand (Peter Sandia) Sat, 19 Dec 2009 13:51:42 -0000
Scholl Advance Athlete's Foot Cream 15g | Wart Removal: NEW.Terbinafine Hydrochloride 1% w/w.RELIEVES THE ITCH... http://bit.ly/5hu1lD

 
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DrugDigest: Terbinafine ( Lamisil ) - Information on dosage, usage, side effects, interactions, and drug comparisons, including generics when available.

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