Tenofovir disoproxil fumarate (TDF), marketed by Gilead Sciences under the trade name Viread®, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (NtRTIs), which block reverse transcriptase, an enzyme crucial to viral production in HIV-infected people.

Tenofovir is also available in a fixed-dose combination with emtricitabine in a product with the brand name Truvada® for once-a-day dosing. (Emtricitabine is marketed as a single-compound product called Emtriva®, also by Gilead.) A fixed-dose triple combination of tenofovir, emtricitabine and efavirenz (Sustiva®, marketed by Bristol-Myers Squibb) is in development.

Tenofovir is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults. This indication is based on analyses of plasma HIV-1 RNA levels and CD4 cell counts in controlled studies of tenofovir in treatment-naïve and treatment-experienced adults. There are no study results demonstrating the effect of tenofovir on clinical progression of HIV.

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Hepatitis: Long-term Studies Show Tenofovir (Viread) Safety and Efficacy Is... http://bit.ly/431zNW
radkamrin (Austina Thornley) Sun, 08 Nov 2009 03:50:53 -0000
Hepatitis: Long-term Studies Show Tenofovir (Viread) Safety and Efficacy Is... http://bit.ly/431zNW
Hepatitis: Long-term Studies Show Tenofovir (Viread) Safety and Efficacy Is... http://bit.ly/Y5Or7
radkamrin (Austina Thornley) Sun, 08 Nov 2009 03:50:53 -0000
Hepatitis: Long-term Studies Show Tenofovir (Viread) Safety and Efficacy Is... http://bit.ly/Y5Or7
2 drugs (tenofovir+FTC) used to treat HIV may also help prevent it... http://tinyurl.com/ye5ghq5
tammiehu11bd (Tammie Howell) Sat, 07 Nov 2009 15:34:49 -0000
2 drugs (tenofovir+FTC) used to treat HIV may also help prevent it... http://tinyurl.com/ye5ghq5
#AASLD coverage on http://www.HIVandHepatitis.com: boceprevir SPRINT1 data; HCV protease inhibitor BI 201335; tenofovir for decomp cirrhosis
HIVandHepatitis (HIVandHepatitis.com) Sat, 07 Nov 2009 06:01:36 -0000
#AASLD coverage on http://www.HIVandHepatitis.com: boceprevir SPRINT1 data; HCV protease inhibitor BI 201335; tenofovir for decomp cirrhosis
Destaca-se que o pedido divisional da patente do Tenofovir deriva de um pedido que já foi indeferida pelo INPI por falta de ativ. inventiva.
franciscoadvbr (Francisco Viegas Nev) Fri, 06 Nov 2009 17:41:40 -0000
Destaca-se que o pedido divisional da patente do Tenofovir deriva de um pedido que já foi indeferida pelo INPI por falta de ativ. inventiva.
Assinaram o subsídio do Tenofovir as seguintes organizações ABIA, Conectas, GAPA-SP, GAPA-RS, GESTOS, GIV, IDEC, FENAFAR, RNP+/NSL.
franciscoadvbr (Francisco Viegas Nev) Fri, 06 Nov 2009 17:40:10 -0000
Assinaram o subsídio do Tenofovir as seguintes organizações ABIA, Conectas, GAPA-SP, GAPA-RS, GESTOS, GIV, IDEC, FENAFAR, RNP+/NSL.

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