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Sumatriptan (Imitrex, Imigran,Imigran Recovery ) is a triptan drug including a sulfonamide group which was originally developed by Glaxo for the treatment of migraine headaches.
Approval and availability
Several dosage forms for sumatriptan have been approved, including tablets, solution for injection, and nasal inhalers. Sumatriptan was the first triptan available (in 1991), and, in the United States and most developed countries, is available only by medical prescription. In the United Kingdom, sumatriptan is available over the counter, under the name of Imigran Recovery. It is sold in packs of two 50mg tablets for approximately £7.99. Larger pack sizes, the nasal spray, and the liquid preparation for injection are still only available by prescription.
Mode of action
Sumatriptan is a 5-HT (5-HT1D) agonist. The specific receptor subtype it activates is present in the cranial and basilar arteries. Activation of these receptors causes vasoconstriction of those dilated arteries. Sumatriptan is also shown to decrease the activity of the trigeminal nerve. More on [ Sumatriptan ]
The left side of my head gives a giant shout-out to the inventors of sumatriptan succinate. (http://www.rxlist.com/imitrex-drug.htm)
lturrentine (Lindsey Turrentine) Thu, 17 Dec 2009 20:39:37 -0000
The left side of my head gives a giant shout-out to the inventors of sumatriptan succinate. (http://www.rxlist.com/imitrex-drug.htm)
For the record: sumatriptan is a beautiful thing. (almost as good as having naturally sufficient serotonin levels.)
stereogab (Gabriela) Thu, 17 Dec 2009 16:16:40 -0000
For the record: sumatriptan is a beautiful thing. (almost as good as having naturally sufficient serotonin levels.)
Free TREXIMET® (sumatriptan and naproxen sodium) Tablets: Free TREXIMET® (sumatriptan and naproxen sodium) Tablets For http://bit.ly/7ykzyi
fullmailbox (fullmailbox) Thu, 17 Dec 2009 10:51:13 -0000
Free TREXIMET® (sumatriptan and naproxen sodium) Tablets: Free TREXIMET® (sumatriptan and naproxen sodium) Tablets For http://bit.ly/7ykzyi
Am testat Imigran (Sumatriptan) pt durere de cap. Desi are un efect vascular clar, la mine NU trece durerea. @%*%*#*^#$
danarm (Dan) Thu, 17 Dec 2009 10:19:00 -0000
Am testat Imigran (Sumatriptan) pt durere de cap. Desi are un efect vascular clar, la mine NU trece durerea. @%*%*#*^#$
Does sumatriptan cross the bloodâbrain barrier in animals and man? http://twurl.nl/bf4e6b
Gron_neurologen (Groninger Neurologen) Wed, 16 Dec 2009 08:09:44 -0000
Does sumatriptan cross the blood–brain barrier in animals and man? http://twurl.nl/bf4e6b
@BobTheSkutter that'll be a migraine then. Have you tried getting a prescription for sumatriptan or eletriptan?
SHM5 (Stephen HellerMurphy) Sun, 13 Dec 2009 10:07:22 -0000
@BobTheSkutter that'll be a migraine then. Have you tried getting a prescription for sumatriptan or eletriptan?
DrugDigest: Sumatriptan ( Imitrex ) - Information on dosage, usage, side effects, interactions, and drug comparisons, including generics when available.
Imitrex - Product information from Glaxo Wellcome, in Portable Document Format (PDF). (sumatriptan succinate)
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Imitrex - Product information for US residents in PDF format. [Acrobat Reader required]
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