Sotalol (Betapace®, Berlex Laboratories) is a drug used in individuals with rhythm disturbances (cardiac arrhythmias) of the heart. It falls into the class of beta blockers (and class II antiarrhythmic agents) because of its primary action on the β-adrenergic receptors in the heart.

In addition to its actions on the beta receptors in the heart, sotalol inhibits the inward potassium ion channels of the heart. In so doing, sotalol prolongs repolarization, therefore lengthening the QT interval and decreasing automaticity. It also slows atrioventricular (AV) nodal conduction. Because of these actions on the cardiac action potential, it is also considered a class III antiarrhythmic agent.

Sotalol is used to treat ventricular tachycardias as well as atrial fibrillation. It may be taken orally, since its bioavailability is almost 100%.

More on [ Sotalol ]

Sotalol - Twitter Search

The SVT is at bay for now, long QTc indicating plenty of Sotalol on board, low Digoxin levels even though he is getting that one in IV. Odd!
mckmama (MckMama) Mon, 02 Nov 2009 00:29:03 -0000
The SVT is at bay for now, long QTc indicating plenty of Sotalol on board, low Digoxin levels even though he is getting that one in IV. Odd!
In ER at Children's. Got IV in on 2nd try. Adenosine twice. Neither worked. Starting IV Sotalol drip & admitting him to PICU. He's sedated.
mckmama (MckMama) Wed, 28 Oct 2009 04:57:57 -0000
In ER at Children's. Got IV in on 2nd try. Adenosine twice. Neither worked. Starting IV Sotalol drip & admitting him to PICU. He's sedated.

Subscribe to Sotalol RSS feed