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Sotalol (Betapace®, Berlex Laboratories) is a drug used in individuals with rhythm disturbances (cardiac arrhythmias) of the heart. It falls into the class of beta blockers (and class II antiarrhythmic agents) because of its primary action on the β-adrenergic receptors in the heart.
In addition to its actions on the beta receptors in the heart, sotalol inhibits the inward potassium ion channels of the heart. In so doing, sotalol prolongs repolarization, therefore lengthening the QT interval and decreasing automaticity. It also slows atrioventricular (AV) nodal conduction. Because of these actions on the cardiac action potential, it is also considered a class III antiarrhythmic agent.
Sotalol is used to treat ventricular tachycardias as well as atrial fibrillation. It may be taken orally, since its bioavailability is almost 100%.
More on [ Sotalol ]
Beta Blockers :: Drugs and Medications
RT @evelienonline De volgende keer als ik Dexter kijk neem ik maar een extra sotalol. Jeetje, wat spannend!
DexterFanWeb (Dexter Fan Web) Mon, 30 Nov 2009 18:28:39 -0000
RT @evelienonline De volgende keer als ik Dexter kijk neem ik maar een extra sotalol. Jeetje, wat spannend!
De volgende keer als ik Dexter kijk neem ik maar een extra sotalol. Jeetje, wat spannend!
evelienonline (evelienonline) Mon, 30 Nov 2009 18:17:22 -0000
De volgende keer als ik Dexter kijk neem ik maar een extra sotalol. Jeetje, wat spannend!
Betapace AF - Information for US consumers and health care professionals including prescribing information, details of its use in the treatment of atrial fibrilation, newsletter, and patient resources.
DrugDigest: Sotalol ( Betapace ) - Information on dosage, usage, side effects, interactions, and drug comparisons, including generics when available.
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