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Granulocyte macrophage colony-stimulating factor, often abbreviated to GM-CSF, is a protein secreted by macrophages that stimulates stem cells to produce granulocytes (neutrophils, eosinophils, and basophils) and macrophages. It is thus part of the immune/inflammatory cascade, whereby activation of a small number of macrophages produces more of them in circulation.

Granulocyte macrophage colony-stimulating factor is distinct from granulocyte colony-stimulating factor.

Also known as sargramostim when the protein is expressed in yeast cells (trademarked Leukine®), granulocyte macrophage colony-stimulating factor is used as a medication to stimulate the production of white blood cells, especially granulocytes and macrophages, following chemotherapy.

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Vaccine Therapy Plus Sargramostim and Chemotherapy in Treating Women With Stage II or Stage III Breast Cancer http://bit.ly/19LuIG
trialscentral (Trials Central) Thu, 05 Nov 2009 17:22:41 -0000
Vaccine Therapy Plus Sargramostim and Chemotherapy in Treating Women With Stage II or Stage III Breast Cancer http://bit.ly/19LuIG
A Patient's Guide to Sargramostim http://bit.ly/1FkULA
knowdrugs (Sunil) Sun, 01 Nov 2009 22:32:08 -0000
A Patient's Guide to Sargramostim http://bit.ly/1FkULA
Vaccine Therapy Plus Sargramostim and Chemotherapy in Treating Women With Stage II or Stage III Breast Cancer http://bit.ly/24Lgrt
trialscentral (Trials Central) Thu, 29 Oct 2009 17:04:19 -0000
Vaccine Therapy Plus Sargramostim and Chemotherapy in Treating Women With Stage II or Stage III Breast Cancer http://bit.ly/24Lgrt

 
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Leukine.com (sargramostim) - Official pharmaceutical website offers information for patients and prescriber.

Sargramostim - Information about dosage, side effects, and other aspects of use of this medication for HIV-related conditions. Brand names include Leukine, Prokine, and GM-CSF.

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