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Ritonavir, with trade name Norvir® (Abbott Laboratories), is an antiretroviral drug from the protease inhibitor class used to treat HIV infection and AIDS.
Ritonavir is frequently prescribed as the protease inhibitor component in HAART because it inhibits the same host enzyme that metabolizes NRTIs and NNRTIs. This inhibition leads to higher plasma concentrations of these latter drugs, allowing the clinician to lower their dose and frequency.
History
Ritonavir is manufactured as Norvir® by Abbott Laboratories. Research that led to the drug's development was financed in part by a $3,500,000 federal grant through the National Institutes of Health (NIH). The Food and Drug Administration (FDA) approved ritonavir on March 1, 1996, making it the seventh approved antiretroviral drug in the United States. In 2003, Abbott raised the price of a Norvir course from USD $1.71 per day to $8.57 per day, leading to claims of price gouging by patients' groups and some members of Congress. Consumer group Essential Inventions petitioned the NIH to override the Norvir patent, but the NIH announced on August 4, 2004 that it would not invoke its legal right to allow generic production of Norvir, citing potential adverse effects on the pharmaceutical market. More on [ Ritonavir ]
úgy tűnik, kisebb norvir (ritonavir) dózis is elég lehet, ami sokkal kevesebb mellékhatást jelentene. http://bit.ly/LfKti
shivamantra (Mantra Shiva) Wed, 04 Nov 2009 23:21:22 -0000
úgy tűnik, kisebb norvir (ritonavir) dózis is elég lehet, ami sokkal kevesebb mellékhatást jelentene. http://bit.ly/LfKti
Darunavir/ritonavir, etravirine and raltegravir has 'remarkable' success in children with resistant virus http://bit.ly/1nwek8
GeneRef (GeneRef) Fri, 30 Oct 2009 02:03:57 -0000
Darunavir/ritonavir, etravirine and raltegravir has 'remarkable' success in children with resistant virus http://bit.ly/1nwek8
carbamazapine may decrease blood levels of HIV meds. Also known toxicity with ritonavir, loprinavir. #aacap
bobfinn (Bob Finn) Thu, 29 Oct 2009 18:12:10 -0000
carbamazapine may decrease blood levels of HIV meds. Also known toxicity with ritonavir, loprinavir. #aacap
Dr. Qazi: RITONAVIR inhibits cell cycle progression in panc-1 cells #iSURGITEC
juliomayol (Julio Mayol) Thu, 29 Oct 2009 14:58:22 -0000
Dr. Qazi: RITONAVIR inhibits cell cycle progression in panc-1 cells #iSURGITEC
DrugDigest: Ritonavir ( Norvir ) - Information on dosage, usage, side effects, interactions, and drug comparisons, including generics when available.
Norvir - a.k.a. Ritonavir
Ritonavir - (Norvir)
Ritonavir ( Norvir ) from Abbott Laboratories - Manufacturer's patient and prescribing information for this HIV medicine.
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