Riluzole is a drug used to treat amyotrophic lateral sclerosis. It delays the onset of ventilator-dependence or tracheostomy in selected patients and may increase survival by approximately two months.

It is marketed by Aventis Pharmaceuticals Inc with the brand name Rilutek.

Mechanism of action

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Riluzole has several actions:

• Sodium channel blockade
• High-voltage calcium channel blockade
• N-methyl-D-aspartate (NMDA)/glutamate receptor blockade

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placebo-controlled riluzole in pediatric bipolar disorder http://bit.ly/8Pv43P
paidtrials (US Clinical Trials) Sun, 06 Dec 2009 05:23:01 -0000
placebo-controlled riluzole in pediatric bipolar disorder http://bit.ly/8Pv43P
riluzole 2 treat child & adolescent obsessive-compulsive disorder w/ or w/o autism spectrum disorders http://bit.ly/5e6Y6s
paidtrials (US Clinical Trials) Sat, 05 Dec 2009 11:12:24 -0000
riluzole 2 treat child & adolescent obsessive-compulsive disorder w/ or w/o autism spectrum disorders http://bit.ly/5e6Y6s
neuroprotection w/ riluzole ppl w/ early multiple sclerosis http://bit.ly/5alEJa
sftrials (sf trials) Thu, 03 Dec 2009 10:45:47 -0000
neuroprotection w/ riluzole ppl w/ early multiple sclerosis http://bit.ly/5alEJa
magnetic resonance spectroscopic examination of children & adolescents taking riluzole 4 obsessive-compulsive disorder http://bit.ly/7W98hG
dctrials (dc trials) Thu, 03 Dec 2009 10:10:59 -0000
magnetic resonance spectroscopic examination of children & adolescents taking riluzole 4 obsessive-compulsive disorder http://bit.ly/7W98hG
riluzole in women w/ stage i, stage ii, or stage iiia breast cancer http://bit.ly/4yrZmW
breastctrials (Breast Cancer Trials) Thu, 03 Dec 2009 07:38:52 -0000
riluzole in women w/ stage i, stage ii, or stage iiia breast cancer http://bit.ly/4yrZmW
riluzole in fragile x syndrome http://bit.ly/5U1Fcy
paidtrials (US Clinical Trials) Thu, 03 Dec 2009 05:18:46 -0000
riluzole in fragile x syndrome http://bit.ly/5U1Fcy

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