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Ribavirin (Copegus®; Rebetol®; Ribasphere®; Vilona®,Virazole®, also generics from Sandoz, Teva, Warrick) is an anti-viral drug which is active against a number of DNA and RNA viruses. It is a member of the nucleoside antimetabolite drugs that interfere with duplication of viral genetic material. Though not effective against all viruses, ribavirin is remarkable as a small molecule for its wide range of activity, including important activities against influenzas, flaviviruses and agents of many viral hemorrhagic fevers.
Ribavirin is a pro-drug, activated by cellular kinases which change it into the 5' triphosphate nucleotide. In this form it interferes with aspects of RNA metabolism related to viral reproduction. A number of mechanisms have been proposed for this (see Mechanisms of Action, below) but none of these is proven. More than one mechanism may be active.
In the U.S. the oral (capsule or tablet) form of ribavirin is used in the treatment of hepatitis C, in combination with interferon drugs. The aerosol form is used to treat respiratory syncytial virus-related diseases in children. In Mexico, ribavirin ("ribavirina") has been sold for use against influenza.
More on [ Ribavirin ]
Idenix Pharma - Phase II Clinical Trial of IDX184 in Combo W/Pegylated Interferon & Ribavirin for Treatment of Hep C http://bit.ly/3ZPHrk
nicoleriv (Nicole Rivera-SMI ) Fri, 06 Nov 2009 20:33:57 -0000
Idenix Pharma - Phase II Clinical Trial of IDX184 in Combo W/Pegylated Interferon & Ribavirin for Treatment of Hep C http://bit.ly/3ZPHrk
I/D Tongue Hyperpigmentation Resulting From Peginterferon Alfa and Ribavirin Combination Therapy: The Journa.. http://bit.ly/1M6RQY
MDLinx (Sandeep Pulim MD) Thu, 05 Nov 2009 15:04:05 -0000
I/D Tongue Hyperpigmentation Resulting From Peginterferon Alfa and Ribavirin Combination Therapy: The Journa.. http://bit.ly/1M6RQY
RT @amvr2medwriter Drug Cocktail for Drug-Resist #H1N1 http://TwitPWR.com/w30/ #oseltamivir #Tamiflu #amantadine #Symmetrel #ribavirin
Wanda_Reese (Wanda Reese) Sun, 01 Nov 2009 01:09:11 -0000
RT @amvr2medwriter Drug Cocktail for Drug-Resist #H1N1 http://TwitPWR.com/w30/ #oseltamivir #Tamiflu #amantadine #Symmetrel #ribavirin
Hepatitis: Peginterferon Alfa-2b or Alfa-2a with Ribavirin for Hepatitis C ... http://bit.ly/2xSisq
radkamrin (Austina Thornley) Thu, 29 Oct 2009 12:39:16 -0000
Hepatitis: Peginterferon Alfa-2b or Alfa-2a with Ribavirin for Hepatitis C ... http://bit.ly/2xSisq
DrugDigest: Ribavirin and Interferon alfa-2b ( Rebetron ) - Information on dosage, usage, side effects, interactions, and drug comparisons, including generics when available.
rapy - Free support service for patients with Hepatitis C who are on Rebetron combination therapy or Intron A.
Rebetron - An overview of important information for patients suffering from hepatitis. Prescribing and product information from Schering-Plough's.
Rebetron - Rebetron is the complete source for information about hepatitis especially hepatitis C, understanding risk factors for hepatitis and management and treatment of hepatitis.
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