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Ribavirin (Copegus®; Rebetol®; Ribasphere®; Vilona®,Virazole®, also generics from Sandoz, Teva, Warrick) is an anti-viral drug which is active against a number of DNA and RNA viruses. It is a member of the nucleoside antimetabolite drugs that interfere with duplication of viral genetic material. Though not effective against all viruses, ribavirin is remarkable as a small molecule for its wide range of activity, including important activities against influenzas, flaviviruses and agents of many viral hemorrhagic fevers.
Ribavirin is a pro-drug, activated by cellular kinases which change it into the 5' triphosphate nucleotide. In this form it interferes with aspects of RNA metabolism related to viral reproduction. A number of mechanisms have been proposed for this (see Mechanisms of Action, below) but none of these is proven. More than one mechanism may be active.
In the U.S. the oral (capsule or tablet) form of ribavirin is used in the treatment of hepatitis C, in combination with interferon drugs. The aerosol form is used to treat respiratory syncytial virus-related diseases in children. In Mexico, ribavirin ("ribavirina") has been sold for use against influenza.
More on [ Ribavirin ]
GI: The Utility of Therapeutic Drug Monitoring for Ribavirin in Patients with Chronic Hepatitis C: Annals of.. http://bit.ly/5WKkJy
MDLinx (Sandeep Pulim MD) Mon, 23 Nov 2009 13:25:07 -0000
GI: The Utility of Therapeutic Drug Monitoring for Ribavirin in Patients with Chronic Hepatitis C: Annals of.. http://bit.ly/5WKkJy
efficacy of actos, lipitor, pegasys & ribavirin in chronic hepatitis c genotype 1 ppl who relapsed or non responded 2 http://bit.ly/6CmSwP
sanantoniotrial (san antonio) Mon, 23 Nov 2009 06:04:48 -0000
efficacy of actos, lipitor, pegasys & ribavirin in chronic hepatitis c genotype 1 ppl who relapsed or non responded 2 http://bit.ly/6CmSwP
viral kinetics & liver gene expression in response 2 ribavirin & peginterferon thrpy of chronic hepatitis c http://bit.ly/4pHF4E
dctrials (dc trials) Mon, 23 Nov 2009 05:03:09 -0000
viral kinetics & liver gene expression in response 2 ribavirin & peginterferon thrpy of chronic hepatitis c http://bit.ly/4pHF4E
Reduced Ribavirin frm 6 to 5 tabs tday,its dosed by bodyweight,but its still a basic equation.If i hadn't i wouldve been too ill to go on.
AlphaRabbit (peter ) Sun, 22 Nov 2009 22:53:32 -0000
Reduced Ribavirin frm 6 to 5 tabs tday,its dosed by bodyweight,but its still a basic equation.If i hadn't i wouldve been too ill to go on.
safety & efficacy of telaprevir in combo w/ peginterferon alfa-2a & ribavirin in ppl co-infected w/ hepatitis c virus & http://bit.ly/84Ox1a
leukemiatrials_ (Leukemia Trials) Sun, 22 Nov 2009 08:37:15 -0000
safety & efficacy of telaprevir in combo w/ peginterferon alfa-2a & ribavirin in ppl co-infected w/ hepatitis c virus & http://bit.ly/84Ox1a
safety & efficacy of telaprevir in combo w/ peginterferon alfa-2a & ribavirin in ppl co-infected w/ hepatitis c virus & http://bit.ly/84Ox1a
leukemia_trials (Leukemia) Sun, 22 Nov 2009 08:37:02 -0000
safety & efficacy of telaprevir in combo w/ peginterferon alfa-2a & ribavirin in ppl co-infected w/ hepatitis c virus & http://bit.ly/84Ox1a
DrugDigest: Ribavirin and Interferon alfa-2b ( Rebetron ) - Information on dosage, usage, side effects, interactions, and drug comparisons, including generics when available.
rapy - Free support service for patients with Hepatitis C who are on Rebetron combination therapy or Intron A.
Rebetron - An overview of important information for patients suffering from hepatitis. Prescribing and product information from Schering-Plough's.
Rebetron - Rebetron is the complete source for information about hepatitis especially hepatitis C, understanding risk factors for hepatitis and management and treatment of hepatitis.
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