Pseudoephedrine is a sympathomimetic amine commonly used as a decongestant. The salts pseudoephedrine hydrochloride and pseudoephedrine sulfate are found in many over-the-counter preparations either as single-ingredient preparations, or more commonly in combination with antihistamines, paracetamol and/or ibuprofen. It is often referred to by consumers as Sudafed, which is the trademark for a common brand of pseudoephedrine hydrochloride.

Unlike antihistamines, which modify the systemic histamine-mediated allergic response, pseudoephedrine only relieves nasal congestion commonly associated with colds or allergies. The advantage of oral pseudoephedrine over topical nasal preparations, such as oxymetazoline, is that it does not cause rebound congestion (rhinitis medicamentosa); however, it is more likely to cause adverse effects including hypertension.

Chemistry

---

Pseudoephedrine is a phenethylamine, and an isomer of ephedrine. Pseudoephedrine is the International Nonproprietary Name (INN) of the (1S,2S)- diastereomer of ephedrine (which has 1R,2S- configuration). Other names are (+)-pseudoephedrine and D-pseudoephedrine. (Reynolds, 1989) The enantiomer (-)-(1R,2R)-Pseudoephedrine has fewer side-effects, fewer central nervous system (CNS) stimulatory effects, does not reduce to d-methamphetamine, and yet retains its efficacy as a decongestant. However, the patent holder for (-)-Pseudoephedrine has not yet sought or received government approval for its sale to the public. (US Patent 6,495,529)

More on [ Pseudoephedrine ]

Pseudoephedrine - Twitter Search

Curse this bloody nasal congestion on my vacation!! At least Houston has the miracle drug - pseudoephedrine, how I adore you!
csharp7 (Caroline Sharp) Wed, 23 Dec 2009 04:02:50 -0000
Curse this bloody nasal congestion on my vacation!! At least Houston has the miracle drug - pseudoephedrine, how I adore you!
Breakfast on Christmas day began with an aperitif of vodka, cranberry juice and household bleach followed by a dozen pseudoephedrine.
toastman (James TOASTMAN) Wed, 23 Dec 2009 03:16:57 -0000
Breakfast on Christmas day began with an aperitif of vodka, cranberry juice and household bleach followed by a dozen pseudoephedrine.
Pseudoephedrine > phenylephrine.
girlboymusic (Cuntballs McFuckface) Wed, 23 Dec 2009 01:14:54 -0000
Pseudoephedrine > phenylephrine.
@thehuxman managed to get my xmas shopping done this morning, pseudoephedrine is a wonderful thing indeed!
Alegrya (Alison Young) Wed, 23 Dec 2009 01:13:34 -0000
@thehuxman managed to get my xmas shopping done this morning, pseudoephedrine is a wonderful thing indeed!
Medical marijuana - so many scream about it being a controlled substance. Um...so is codeine. So is most pseudoephedrine (Sudafed). So is...
Tokkar (wtb Sanity) Wed, 23 Dec 2009 00:33:07 -0000
Medical marijuana - so many scream about it being a controlled substance. Um...so is codeine. So is most pseudoephedrine (Sudafed). So is...
An Ord. requiring a prescription to purchase products containing pseudoephedrine in Poplar Bluff has been passed by the city council.
pbpd (Poplar Bluff PD) Tue, 22 Dec 2009 23:51:58 -0000
An Ord. requiring a prescription to purchase products containing pseudoephedrine in Poplar Bluff has been passed by the city council.

Subscribe to Pseudoephedrine RSS feed