Protamines are small, arginine-rich, nuclear proteins that replace histones late in the haploid phase of spermatogenesis and are believed essential for sperm head condensation and DNA stabilization. Mice, humans, and certain fish have 2 or more different protamines, whereas the sperm of bull, boar, rat, rabbit, guinea pig, and ram have one form of protamine. The 2 human protamines are denoted PRM1 and PRM2.

When mixed with insulin, protamines slow down the onset and duration of insulin action (see NPH insulin).

See also

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• Protamine sulfate

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#WW Has your veterinarian prescribed #compounded Protamine Zinc Insulin (PZI) for your dog or cat? Learn more at http://t.co/nxkKI4xD
WedgewoodPetRx (Wedgewood Pharmacy) Tue, 07 Feb 2012 20:33:29 -0000
#WW Has your veterinarian prescribed #compounded Protamine Zinc Insulin (PZI) for your dog or cat? Learn more at http://t.co/nxkKI4xD
#WW Has your veterinarian prescribed #compounded Protamine Zinc Insulin (PZI) for your dog or cat? Learn more at http://t.co/nxkKI4xD
WedgewoodPetRx (Wedgewood Pharmacy) Sat, 04 Feb 2012 12:49:34 -0000
#WW Has your veterinarian prescribed #compounded Protamine Zinc Insulin (PZI) for your dog or cat? Learn more at http://t.co/nxkKI4xD
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