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Propranolol (INN) (IPA: ) is a non-selective beta blocker mainly used in the treatment of hypertension. It was the first successful beta blocker developed. Propranolol is commonly marketed by AstraZeneca under the trade name Inderal.

History and development


Scottish scientist James W. Black successfully developed propranolol in the late 1950s. He was awarded the Nobel Prize in Medicine for this discovery in 1988.

Propranolol was developed from the early β-adrenergic antagonists dichloroisoprenaline and pronethalol. The key structural modification, which was carried through to essentially all subsequent beta blockers, was the insertion of an oxymethylene bridge into the arylethanolamine structure of pronethalol thus greatly increasing the potency of the compound. This also apparently eliminated the carcinogenicity found with pronethalol in animal models.

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Beta Blockers :: Drugs and Medications

 
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@marcialima Só propranolol.
marcelolimas (Marcelo Bio) Tue, 15 Dec 2009 13:31:28 -0000
@marcialima Só propranolol.
ik word fucking high van propranolol, en misselijk, en koude handen EN RAAD EENS WIE ER NOG STEEDS DAGELIJKS HOOFDPIJN HEEFT? ik haat het
marjoleinW (Marjolein ) Mon, 14 Dec 2009 18:28:41 -0000
ik word fucking high van propranolol, en misselijk, en koude handen EN RAAD EENS WIE ER NOG STEEDS DAGELIJKS HOOFDPIJN HEEFT? ik haat het
Generic propranolol 80mg online « Dr Zord's Blog http://bit.ly/8VCXBW
Past40 (Di Wilson) Sun, 13 Dec 2009 19:44:28 -0000
Generic propranolol 80mg online « Dr Zord's Blog http://bit.ly/8VCXBW
@jcasco Tudo bem sim, estou um pouco nervosa com as provas finais....preciso de um propranolol 10...rss
lorenazam (Lorena ) Sun, 13 Dec 2009 01:45:31 -0000
@jcasco Tudo bem sim, estou um pouco nervosa com as provas finais....preciso de um propranolol 10...rss
ptsd symptom reduction by propranolol given after trauma memory activation http://bit.ly/8d19kn
paidtrials (US Clinical Trials) Sat, 12 Dec 2009 04:34:54 -0000
ptsd symptom reduction by propranolol given after trauma memory activation http://bit.ly/8d19kn
No spoilers, but on Bones last night, bomber was pumped full of propranolol - talked about its use by criminals -just odd since I'm on it
eileen53 (Aprille E) Fri, 11 Dec 2009 14:20:46 -0000
No spoilers, but on Bones last night, bomber was pumped full of propranolol - talked about its use by criminals -just odd since I'm on it

 
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DrugDigest: Propranolol ( Inderal ) - Information on dosage, usage, side effects, interactions, and drug comparisons, including generics when available.

Inderal - Propranolol HCl. Prescribing information and warnings for US residents in PDF format. [Acrobat Reader required]

Inderal LA - Propranolol HCl. Prescribing information and warnings for US residents in PDF format. [Acrobat Reader required]

Inderide - Propranolol HCl and hydrochlorothiazide. Prescribing information for US residents in PDF format. [Acrobat Reader required]

Inderide LA - Propranolol HCl and hydrochlorothiazide. Prescribing information for US residents in PDF format. [Acrobat Reader required]

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