Propranolol (INN) (IPA: ) is a non-selective beta blocker mainly used in the treatment of hypertension. It was the first successful beta blocker developed. Propranolol is commonly marketed by AstraZeneca under the trade name Inderal.

History and development

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Scottish scientist James W. Black successfully developed propranolol in the late 1950s. He was awarded the Nobel Prize in Medicine for this discovery in 1988.

Propranolol was developed from the early β-adrenergic antagonists dichloroisoprenaline and pronethalol. The key structural modification, which was carried through to essentially all subsequent beta blockers, was the insertion of an oxymethylene bridge into the arylethanolamine structure of pronethalol thus greatly increasing the potency of the compound. This also apparently eliminated the carcinogenicity found with pronethalol in animal models.

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SONO XTREME e o PISC nervoso voltou A MIL. NÂO to afim de tomar o DOBRO de propranolol pra evitar saturar de vez essa %#@$%¨#$&# de remédio!
LOLkito (Renan L.B) Fri, 06 Nov 2009 22:58:24 -0000
SONO XTREME e o PISC nervoso voltou A MIL. NÂO to afim de tomar o DOBRO de propranolol pra evitar saturar de vez essa %#@$%¨#$&# de remédio!
Determination of the binding sites of propranolol hcl on bovine serum albumin by direct & reverse procedures http://kele.es/iB0
Sciencia (Webmaster Sciencia) Fri, 06 Nov 2009 07:30:49 -0000
Determination of the binding sites of propranolol hcl on bovine serum albumin by direct & reverse procedures http://kele.es/iB0
Generic Inderal (Propranolol 10/20/40/80mg) http://tr.im/EhRt Cardiovascular, arrhythmias, angina, heart attack
_Generic (Your online pharmacy) Fri, 06 Nov 2009 01:41:14 -0000
Generic Inderal (Propranolol 10/20/40/80mg) http://tr.im/EhRt Cardiovascular, arrhythmias, angina, heart attack
Anxiety Attacks Medications—An Overview Of Beta Blockers: Propranolol (Inderal) should be kept away from the re.. http://bit.ly/4qzRHt
_Panic_Attacks_ (Jonathan Hawley) Wed, 04 Nov 2009 14:05:31 -0000
Anxiety Attacks Medications—An Overview Of Beta Blockers: Propranolol (Inderal) should be kept away from the re.. http://bit.ly/4qzRHt
E o Propranolol não funciona mais em mim... maldição. note to self: need stronger drugs. ¬¬
LOLkito (Renan L.B) Wed, 04 Nov 2009 11:35:03 -0000
E o Propranolol não funciona mais em mim... maldição. note to self: need stronger drugs. ¬¬
Why does propranolol taste so bad? I end up spitting it out. Disgusting.
GinnyGragg (ginny gragg) Wed, 04 Nov 2009 03:02:37 -0000
Why does propranolol taste so bad? I end up spitting it out. Disgusting.

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