Prednisone is a synthetic corticosteroid drug which is usually taken orally and can be used for a large number of different conditions. It has a mainly glucocorticoid effect. Prednisone is a prodrug that is converted by the liver into prednisolone, which is the active drug and a steroid.

Uses

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Prednisone is particularly effective as an immunosuppressant and affects virtually all of the immune system. It can therefore be used in autoimmune diseases, inflammatory diseases (such as asthma, severe poison ivy, and Crohn's disease), various kidney diseases including nephrotic syndrome, and to prevent and treat rejection in organ transplantation.

History

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Prednisone was invented in the early 1950s when Arthur Nobile (1920 - 2004) at Schering demonstrated that the side effects of cortisone such as water retention, high blood pressure and muscle weakness could be removed by oxidisation of the drug through exposure to microbes. The drug was introduced by Schering in the mid-1960s.

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Is a firm believer that Prednisone should have something to prevent the AWFUL aftertaste.
danac78 (Dana Haywood) Fri, 11 Dec 2009 21:55:53 -0000
Is a firm believer that Prednisone should have something to prevent the AWFUL aftertaste.
Oh my gosh...I hate how prednisone makes me feel!!!!
jesusluvsu2 (Alexandra Nicole) Fri, 11 Dec 2009 21:53:07 -0000
Oh my gosh...I hate how prednisone makes me feel!!!!
didn't realize how round my face got from the prednisone till i see it in pictures... wow
ssamantha_anne (Samantha Perrelli) Fri, 11 Dec 2009 21:23:30 -0000
didn't realize how round my face got from the prednisone till i see it in pictures... wow
Anyone got any non-quacky tips for living while on prednisone? @jdc325?
Amanda_Rudelt (Amanda_Rudelt) Fri, 11 Dec 2009 19:12:08 -0000
Anyone got any non-quacky tips for living while on prednisone? @jdc325?
Prednisone makes me feel like I could eat an entire cow for lunch...I hope that feeling goes away after just a few bites!
oheisner (Osann Heisner) Fri, 11 Dec 2009 18:00:00 -0000
Prednisone makes me feel like I could eat an entire cow for lunch...I hope that feeling goes away after just a few bites!
60 mg. Prednisone + surly bastard = http://www.tubechop.com/watch/32207 May God help you all!
oberata (Jeff Timpanaro) Fri, 11 Dec 2009 17:55:32 -0000
60 mg. Prednisone + surly bastard = http://www.tubechop.com/watch/32207 May God help you all!

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