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Pimecrolimus is an immunomodulating agent used in the treatment of atopic dermatitis (eczema). It is currently available as a topical cream, marketed by Novartis, under the trade name Elidel.
Pharmacology
Pimecrolimus is an ascomycin macrolactam derivative. It has been shown in vitro that pimecrolimus binds to macrophilin-12 and inhibits calcineurin. Thus pimecrolimus inhibits T-cell activation by inhibiting the synthesis and release of cytokines from T-cells. Pimecrolimus also prevents the release of inflammatory cytokines and mediators from mast cells.
Side effects
More on [ Pimecrolimus ]
10 year registry of children w/ eczema tht have used pimecrolimus http://bit.ly/5e9jZd
lymphomatrial (localclinicaltrials) Thu, 03 Dec 2009 04:39:42 -0000
10 year registry of children w/ eczema tht have used pimecrolimus http://bit.ly/5e9jZd
Elidel (pimecrolimus) Novartis - Canada - This site offers the approved Canadian patient and prescribing information for Elidel, as well as links to related press releases and eczema resources.
Meta Description: [ Canadian patient and prescribing information for Elidel from Novartis Pharmaceuticals Canada Inc. ]
Elidel Eczema Treatment - Official pharmaceutical website with information for patients and health professionals.
Meta Description: [ Learn about treatment of mild to moderate eczema with Elidel. Find out how to tell when skin rashes may be eczema, and how to take care of itchy skin. ]
Food and Drug Administration (FDA) - Elidel Consumer Information - Patient FAQ in html format with a link to approved labeling (as pdf).b
Pimecrolimus (Topical) - Healthtouch - Information for consumers in html format.
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