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Phentolamine is a competitive nonselective alpha adrenergic receptor antagonist. When given by injection causes blood vessels to expand, thereby increasing blood flow. When injected into the penis (intracavernosal), it increases blood flow to the penis, which results in an erection.
It's primary stocking purpose in hospitals is in crash carts to counteract severe peripheral vasoconstriction secondary to extravasation of peripherally placed vasopressor infusions, such as nor-epinephrine primarily and alpha 1 (one) agonist, vasopressin, etc. Epinephrine (or Adrenaline) infusions are less vasoconstrictive then nor-epinephrine (or noradrenaline) due to the primary beta receptor stimulation before alpha but remains dose dependent.
More on [ Phentolamine ]
Phentolamine Mesylate is a vasodilator (alpha adrenergic antagonist) and LA reversal agent http://myloc.me/1xumC
extractionista (Safa Maiwand, DDS) Mon, 16 Nov 2009 17:09:18 -0000
Phentolamine Mesylate is a vasodilator (alpha adrenergic antagonist) and LA reversal agent http://myloc.me/1xumC
Answer: 1. Tincture of time, ie supportive care and observation preferred 2. Lidocaine to vasodilate 3. Phentolamine as a last resort.
cooneyrr (cooneyrr) Fri, 13 Nov 2009 03:50:14 -0000
Answer: 1. Tincture of time, ie supportive care and observation preferred 2. Lidocaine to vasodilate 3. Phentolamine as a last resort.
@cooneyrr finger infarction unlikely but can use phentolamine as a rescue if you accidently inject lido with epi in a digit.
shookdocs (Britt & Ryan Shook) Wed, 11 Nov 2009 16:19:01 -0000
@cooneyrr finger infarction unlikely but can use phentolamine as a rescue if you accidently inject lido with epi in a digit.
Phentolamine (Intracavernosal) - MedlinePlus - Brief Summary for consumers from the National Library of Medicine.
Meta Description: [ Phentolamine (Intracavernosal) ]
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