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Oxcarbazepine (Marketed as Trileptal® by Novartis) is an anticonvulsant and mood stabilizing drug, used primarily in the treatment of epilepsy and bipolar disorder.

Oxcarbazepine is structurally a derivative of carbamazepine, adding an extra oxygen atom to the benzylcarboxamide group. This difference helps reduce the impact on the liver of metabolizing the drug, and also prevents the serious forms of anemia occasionally associated with carbamazepine. Aside from this reduction in side effects, it is thought to have the same mechanism as carbamazepine - sodium channel inhibition - and is generally used to treat the same conditions.

Side effects


Oxcarbazepine occasionally causes fatigue, nausea, vomiting, headache, dizziness, drowsiness, and blurred or double vision. It can cause hyponatremia, so blood sodium levels should be tested if the patient complains of severe fatigue. Along with these side effects, pseudo side effects have also been that of desires for salty food, i.e. potato chips.

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500 Trileptal - Provides product information for US residents and healthcare professionals as well as epilepsy resources. Password protected area for non-US professionals.
Meta Description: [ Learn about epileptic seizures, what causes epilepsy, and seizure types. Read about a medication for the treatment of partial seizures caused by epilepsy. ]

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