Gourt > Health > Pharmacy > Drugs and Medications > O > Oxaliplatin
.gif | width = 166 | CAS_number = 63121-00-6 | ATC_prefix = L01 | ATC_suffix = XA03 | ATC_supplemental = | PubChem = 77994 | DrugBank = APRD00186 | chemical_formula = C8H12N2O4Pt | molecular_weight = 395.27 g/mol | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | pregnancy_category = | legal_status = | routes_of_administration = Intravenous | excretion = Renal }} Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. It is typically administered in combination with fluorouracil and leucovorin in a combination known as FOLFOX for the treatment of colorectal cancer. Compared to cisplatin the two amine groups are replaced by cyclohexyldiamine for improved antitumour activity. The chlorine ligands are replaced by the oxalato bidentate derived from oxalic acid in order to improve water solubility.
Oxaliplatin is marketed by Sanofi-Aventis under the trademark Eloxatin®.
Mechanism of action and efficacy
More on [ Oxaliplatin ]
Heme/Onc: Phase II study of oxaliplatin plus S-1 as first-line treatment for advanced gastric cancer (G-SOX study): Anna http://url4.eu/hjMZ
MDLinx (Sandeep Pulim MD) Fri, 06 Nov 2009 09:16:18 -0000
Heme/Onc: Phase II study of oxaliplatin plus S-1 as first-line treatment for advanced gastric cancer (G-SOX study): Anna http://url4.eu/hjMZ
Oxaliplatin & Leucovorin infusing.. now starts chemo-session #2..
melsocal (melsocal) Thu, 05 Nov 2009 18:40:29 -0000
Oxaliplatin & Leucovorin infusing.. now starts chemo-session #2..
#pharma Oxaliplatin induces apoptosis in hepatocellular carcinoma cells and inhibits tumor growth: Exper.. http://bit.ly/2c8FhM
ExpertOpinion (Expert Opinion) Thu, 05 Nov 2009 07:07:08 -0000
#pharma Oxaliplatin induces apoptosis in hepatocellular carcinoma cells and inhibits tumor growth: Exper.. http://bit.ly/2c8FhM
Clinical Trial of Gemcitabine and Oxaliplatin in Recurrent or Metastatic Breast Cancer http://bit.ly/1IWzMh
trialscentral (Trials Central) Tue, 03 Nov 2009 18:19:51 -0000
Clinical Trial of Gemcitabine and Oxaliplatin in Recurrent or Metastatic Breast Cancer http://bit.ly/1IWzMh
Clinical Trial of Gemcitabine and Oxaliplatin in Recurrent or Metastatic Breast Cancer http://bit.ly/73xv1
trialscentral (Trials Central) Fri, 30 Oct 2009 17:28:18 -0000
Clinical Trial of Gemcitabine and Oxaliplatin in Recurrent or Metastatic Breast Cancer http://bit.ly/73xv1
Oxaliplatin Promotes the Survival of Drug-Resistant Colon Tumor Cells - http://tinyurl.com/oj8a52
clinic_en (Hospital ClÃnic) Fri, 30 Oct 2009 14:26:10 -0000
Oxaliplatin Promotes the Survival of Drug-Resistant Colon Tumor Cells - http://tinyurl.com/oj8a52
Eloxatin - Sanofi - Eloxatin is a third-generation, platinum-based anti-cancer agent. Indicated in advanced colorectal cancer when used in combination with 5-fluorouracil (5-FU) and leucovorin.
Meta Description: [ Eloxatin (oxaliplatin for injection), in combination with conventional chemotherapy, is used as an adjuvant treatment for patients with stage III colon cancer. Eloxatin is also a first-line therapy to treat advanced colorectal cancer. ]
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