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.gif | width = 166 | CAS_number = 63121-00-6 | ATC_prefix = L01 | ATC_suffix = XA03 | ATC_supplemental = | PubChem = 77994 | DrugBank = APRD00186 | chemical_formula = C8H12N2O4Pt | molecular_weight = 395.27 g/mol | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | pregnancy_category = | legal_status = | routes_of_administration = Intravenous | excretion = Renal }} Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. It is typically administered in combination with fluorouracil and leucovorin in a combination known as FOLFOX for the treatment of colorectal cancer. Compared to cisplatin the two amine groups are replaced by cyclohexyldiamine for improved antitumour activity. The chlorine ligands are replaced by the oxalato bidentate derived from oxalic acid in order to improve water solubility.
Oxaliplatin is marketed by Sanofi-Aventis under the trademark Eloxatin®.
Mechanism of action and efficacy
More on [ Oxaliplatin ]
Study showed oxaliplatin improved colon ... - Health Insurance News: Stage III colon cancer patients Ñn thе gene... http://t.co/Uqh2QIq6
Karinadaily (Karina Daily) Tue, 24 Jan 2012 14:17:50 -0000
Study showed oxaliplatin improved colon ... - Health Insurance News: Stage III colon cancer patients іn thе gene... http://t.co/Uqh2QIq6
University of Virginia study shows oxaliplatin improves colon cancer patient survival: http://t.co/RBw1F7HS
cancer_network (Cancer News Network) Tue, 24 Jan 2012 14:00:41 -0000
University of Virginia study shows oxaliplatin improves colon cancer patient survival: http://t.co/RBw1F7HS
Comparative Effectiveness of Oxa
Eloxatin - Sanofi - Eloxatin is a third-generation, platinum-based anti-cancer agent. Indicated in advanced colorectal cancer when used in combination with 5-fluorouracil (5-FU) and leucovorin.
Meta Description: [ Eloxatin (oxaliplatin for injection), in combination with conventional chemotherapy, is used as an adjuvant treatment for patients with stage III colon cancer. Eloxatin is also a first-line therapy to treat advanced colorectal cancer. ]
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