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Octreotide (brand name Sandostatin, Novartis Pharmaceuticals) is an octopeptide that mimics natural somatostatin pharmacologically, though is a more potent inhibitor of growth hormone, glucagon, and insulin than the natural hormone.
Effects
Somatostatin has numerous physiological effects:
- It inhibits secretion of many hormones, such as gastrin, cholecystokinin, glucagon, growth hormone, insulin, secretin, pancreatic polypeptide, and vasoactive intestinal peptide.
- It reduces secretion of fluids by the intestine and pancreas.
- It reduces gastrointestinal motility and inhibits contraction of the gallbladder.
- It inhibits the secretion of certain hormones from the anterior pituitary.
Uses
The Food and Drug Administration (FDA) has approved the usage of a salt form of this peptide, octreotide acetate, as an injectable depot formulation for the treatment of acromegaly, the treatment of diarrhea and flushing episodes associated with carcinoid syndrome, and treatment of diarrhea in patients with vasoactive intestinal peptide-secreting tumors (VIPomas). More on [ Octreotide ]
octreotide & interferon alfa-2b or bvacizumab in treating ppl w/ metastatic or locally advanced, high-risk http://bit.ly/5ZMZa5
paidtrials (US Clinical Trials) Fri, 11 Dec 2009 07:26:53 -0000
octreotide & interferon alfa-2b or bvacizumab in treating ppl w/ metastatic or locally advanced, high-risk http://bit.ly/5ZMZa5
lx1606 in ppl w/ symptomatic carcinoid syndrome not managed by stable-dose octreotide thrpy http://bit.ly/7SuYoq
localtrials (US Clinical Trials ) Wed, 09 Dec 2009 08:18:53 -0000
lx1606 in ppl w/ symptomatic carcinoid syndrome not managed by stable-dose octreotide thrpy http://bit.ly/7SuYoq
lx1606 in ppl w/ symptomatic carcinoid syndrome not managed by stable-dose octreotide thrpy http://bit.ly/7SuYoq
usclinicaltrial (US Clinical Trials) Wed, 09 Dec 2009 07:54:56 -0000
lx1606 in ppl w/ symptomatic carcinoid syndrome not managed by stable-dose octreotide thrpy http://bit.ly/7SuYoq
lx1606 in ppl w/ symptomatic carcinoid syndrome not managed by stable-dose octreotide thrpy http://bit.ly/7SuYoq
recruitingtrial (Recruiting Trials) Wed, 09 Dec 2009 06:02:57 -0000
lx1606 in ppl w/ symptomatic carcinoid syndrome not managed by stable-dose octreotide thrpy http://bit.ly/7SuYoq
efficacy & safety octreotide implant in ppl w/ acromegaly http://bit.ly/4tDrT4
paidtrials (US Clinical Trials) Sat, 05 Dec 2009 16:15:09 -0000
efficacy & safety octreotide implant in ppl w/ acromegaly http://bit.ly/4tDrT4
pharmacokinetics, efficacy & safety of octreotide implant in ppl w/ carcinoid syndrome http://bit.ly/4YGWyF
cancertrials_ (Cancer Trials) Sat, 05 Dec 2009 11:19:08 -0000
pharmacokinetics, efficacy & safety of octreotide implant in ppl w/ carcinoid syndrome http://bit.ly/4YGWyF
Octreotide - Familydoctor.org - Information for patients in English and Spanish.
Octreotide acetate - Has similar effects to a natural hormone called somatostatin and is given by injection. Sandostatin suppresses growth hormone. It is used to treat flushing and diarrhea associated with certain tumors.(Sandostatin)
Octreotide IM injection ( Sandostatin LAR ) - International site for this medication used for Acromegaly. Includes information on Acromegaly, GEP tumors, case studies, physicians roster, journal articles, and slide library.
Meta Description: [ Novartis Pharma provides information on Sandostatin LAR (octreotide/IM injection), the most prescribed and most studied medical therapy in the treatment of acromegaly and gastro-entero-pancreatic neuroendocrine (GEP NE) tumors. Find general information about Sandostatin LAR as well as gain access... ]
Sandostatin LAR ( Octreotide Acetate Injection ) By Norvartis - Both patient and professional information about Acromegaly and GEP tumors and treatment with Sandostatin LAR Depot. Directed towards US residents.
Meta Description: [ Sandostatin LAR Depot and Acromegaly and Carcinoid Syndrome - acromegaly symptoms, carcinoid tumor, and controlling hypersecretion. Gain a better understanding of how Sandostatin LAR Depot works. ]
