Norepinephrine (INN) or noradrenaline (BAN) is a catecholamine and a phenethylamine with chemical formula C₈H₁₁NO₃. The natural stereoisomer is L-(−)-(R)-norepinephrine. It is released from the medulla of the adrenal glands as a hormone into the blood, but it is also a neurotransmitter in the nervous system where it is released from noradrenergic neurons during synaptic transmission. As a stress hormone, it affects parts of the human brain where attention and impulsivity are controlled. Along with epinephrine, this compound affects the fight-or-flight response, activating the sympathetic nervous system to directly increase heart rate, release energy from fat, and increase muscle readiness.

The host of physiological changes activated by a stressful event are unleashed in part by activation of a nucleus in the brain stem called the locus ceruleus. This nucleus is the origin of most norepinephrine pathways in the brain. Neurons using norepinephrine as their neurotransmitter project bilaterally from the locus ceruleus along distinct pathways to the cerebral cortex, limbic system, and the spinal cord, among other projections.

At synapses it acts on both alpha and beta adrenoreceptors.

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Marital conflict causes a rise in stress hormones such as epinephrine, ACTH, growth hormone and norepinephrine.
CounselorBarb (Barbara LoFrisco) Sun, 08 Nov 2009 15:40:07 -0000
Marital conflict causes a rise in stress hormones such as epinephrine, ACTH, growth hormone and norepinephrine.
@the P3's all about norepinephrine. That's what all the cool kids think nowadays anyway.
cwnsaville (cwnsaville) Sat, 07 Nov 2009 18:56:37 -0000
@the P3's all about norepinephrine. That's what all the cool kids think nowadays anyway.
Love n sex are reflected in the brain through activations of neurotransmitters such as dopamine n norepinephrine. #cycling
racegirl_ (Donelys) Fri, 06 Nov 2009 22:11:40 -0000
Love n sex are reflected in the brain through activations of neurotransmitters such as dopamine n norepinephrine. #cycling
Your adrenals need plenty of both Vit. D and omega-3 fat in order to make their stress-fighting adrenaline and norepinephrine.
balancetraining (Megan Valente) Fri, 06 Nov 2009 22:01:28 -0000
Your adrenals need plenty of both Vit. D and omega-3 fat in order to make their stress-fighting adrenaline and norepinephrine.
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jackiesv57n (Jackie Sanders) Fri, 06 Nov 2009 14:29:45 -0000
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