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Systematic name 3-Pyridinecarboxylic acid
Chemical formula C6H5NO2
Molecular mass 123.11 g/mol
Density x.xxx g/cm3
Melting point 236.6 °C
Boiling point xx.x °C
CAS number *
SMILES xxxx
Chemical infobox
Niacin, also known as nicotinic acid or vitamin B3, is a water-soluble vitamin whose derivatives such as NADH, NAD, NAD+, and NADP play essential roles in energy metabolism in the living cell and DNA repair. The designation vitamin B3 also includes the amide form, nicotinamide or niacinamide. Severe lack of niacin causes the deficiency disease pellagra, whereas a mild deficiency slows down the metabolism decreasing cold tolerance. The recommended daily allowance of niacin is 2-12 mg a day for children, 14 mg a day for women, 16 mg a day for men, and 18 mg a day for pregnant or breast-feeding women.

Discovery


Nicotinic acid was first discovered from the oxidation of nicotine. When the properties of nicotinic acid were discovered, it was thought prudent to choose a name to dissociate it from nicotine and to avoid the idea that either smoking provided vitamins or that wholesome food contained a poison. The resulting name 'niacin' was derived from nicotinic acid + vitamin.

Industrial use


Nicotinic acid reacts with hemoglobin and myoglobin in meat to form a brightly coloured complex, and thus has been used as a food additive, typically to improve the colour of minced (ground) meat. Niacin is licensed as a food colouring agent in some, non-European, countries.

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Lipid Lowering Agents :: Drugs and Medications

 
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Taking nicotinic acid in addition to statins actually leads to fewer heart attacks http://bit.ly/tinV7
lorygold (Lory Gold) Sun, 08 Nov 2009 09:33:04 -0000
Taking nicotinic acid in addition to statins actually leads to fewer heart attacks http://bit.ly/tinV7
Statins may be taken alone or with other cholesterol medicines such as fibric acid derivatives bile acid sequestrants or nicotinic acid #FB
mrcmv (charles varner) Fri, 06 Nov 2009 16:06:13 -0000
Statins may be taken alone or with other cholesterol medicines such as fibric acid derivatives bile acid sequestrants or nicotinic acid #FB
Nicotinic acid cuts atherosclerosis in statin-treated patients - from Reuters Health/TDC http://snurl.com/t2th4
doctorschannel (The Doctor's Channel) Thu, 05 Nov 2009 19:57:04 -0000
Nicotinic acid cuts atherosclerosis in statin-treated patients - from Reuters Health/TDC http://snurl.com/t2th4
@shoes_off @lindsayevans I used to buy No Doz Plus (with 10mg of Nicotinic Acid) = $4.99/10 These things at Coles work out at $0.50/10
ozdj (Derek Jenkins) Wed, 04 Nov 2009 06:25:08 -0000
@shoes_off @lindsayevans I used to buy No Doz Plus (with 10mg of Nicotinic Acid) = $4.99/10 These things at Coles work out at $0.50/10

 
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Nicotinic Acid (Niacin) - Information about action as a lipid-lowering agent, side effects, contraindications, and other pharmacologic details.

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