.png | CAS_number = 1404-04-2 | ATC_prefix = A01 | ATC_suffix = AB08 | ATC_supplemental = , , , , , , , | PubChem = 8378 | DrugBank = APRD00013 | chemical_formula = C₂₃H₄₆N₆O₁₃ | molecular_weight = 614.644 g/mol | bioavailability = | protein_bound = | metabolism = | elimination_half-life = 2 to 3 hours | pregnancy_category = | legal_status = | routes_of_administration = }} Neomycin is an aminoglycoside antibiotic that is found in many topical medications such as creams, ointments and eyedrops.

Uses

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Neomycin is overwhelmingly used as a topical preparation. It can also be given orally, where it is usually combined with other antibiotics. Neomycin is not absorbed from the gastrointestinal tract, and has been used as a preventative measure for hepatic encephalopathy and hypercholesterolemia. By killing bacteria in the intestinal tract, it keeps ammonia levels low and prevents hepatic encephalopathy, especially prior to GI surgery. It is not given intravenously, as neomycin is extremely nephrotoxic (it causes kidney damage), especially compared to other aminoglycosides. The exception to this, is when it is included in some vaccines as a preservative, but in very small quantities -typically 0.025 mg per dose^*.

Spectrum

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Similar to other aminoglycosides, neomycin has excellent activity against Gram negative bacteria, and has partial activity against Gram positive bacteria. It is relatively toxic to humans, and some people have allergic reactions to it. See: Hypersensitivity.

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@PoodleBerry They gave me Amoxicillin and Clauvulanate Potassium tablets and Neomycin and Polymxin B Sulfates
itsdarryldsmith (Darryl D. Smith) Fri, 06 Nov 2009 05:12:49 -0000
@PoodleBerry They gave me Amoxicillin and Clauvulanate Potassium tablets and Neomycin and Polymxin B Sulfates
Neomycin sulfate + Polymyxin b sulfate: I feel like it is really drying my eyes out. I continue to drink plenty of... http://bit.ly/1XwM1Z
RateADrug (RateADrug) Wed, 04 Nov 2009 22:49:49 -0000
Neomycin sulfate + Polymyxin b sulfate: I feel like it is really drying my eyes out. I continue to drink plenty of... http://bit.ly/1XwM1Z
E1 w/ reactions to Neosporin (neomycin), do not get either the seasonal or the H1N1. my public svc announcement for the day :)
iconnie11 (Connie Hunnicutt) Wed, 04 Nov 2009 00:18:04 -0000
E1 w/ reactions to Neosporin (neomycin), do not get either the seasonal or the H1N1. my public svc announcement for the day :)
Prodisala! Veliko hvala DurofilinR, Bisolvon, Dexamethason-neomycin, Dexason, Fluimucil. Poruka folowerima: ne zezajte se sa grip(ovima).
dijica (Lidija Stojcic) Sat, 31 Oct 2009 09:18:16 -0000
Prodisala! Veliko hvala DurofilinR, Bisolvon, Dexamethason-neomycin, Dexason, Fluimucil. Poruka folowerima: ne zezajte se sa grip(ovima).

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