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Naltrexone is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence. It is marketed as its hydrochloride salt, naltrexone hydrochloride, under the trade name Revia. In some countries, an extended-release formulation is marketed under the trade name Vivitrol.

Chemical Structure


Naltrexone can be described as a substituted oxymorphone – here the tertiary amine methyl-substituent is replaced with methylcyclopropane.

Pharmacology


Naltrexone, and its active metabolite 6-β-naltrexol, are competitive antagonists at μ- and κ-opioid receptors, and to a lesser extent at δ-opioid receptors. This blockade of opioid receptors is the basis behind its action in the management of opioid dependence—it reversibly blocks or attenuates the effects of opioids.

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Losing the battle, might need Naltrexone again for awhile
ericabasnicki (Erica Basnicki) Sat, 07 Nov 2009 22:39:16 -0000
Losing the battle, might need Naltrexone again for awhile
#Naltrexone no #MS flareups for 24 yrs & no side effects (via @havaneese)
bobthomson70 (bobthomson70) Sat, 07 Nov 2009 17:55:54 -0000
#Naltrexone no #MS flareups for 24 yrs & no side effects (via @havaneese)
RT @JuliaS1573 when I started taking low dose naltrexone,7/08 pharmacist said she ordered it in just 4 me. This wk she said has "lots" on it
bobthomson70 (bobthomson70) Sat, 07 Nov 2009 17:55:41 -0000
RT @JuliaS1573 when I started taking low dose naltrexone,7/08 pharmacist said she ordered it in just 4 me. This wk she said has "lots" on it
@JuliaS1573 when I started taking low dose naltrexone, 7/08 pharmacist said she ordered it in just 4 me. This wk she said has "lots" on it.
nobleday (Nancy Day) Sat, 07 Nov 2009 00:24:37 -0000
@JuliaS1573 when I started taking low dose naltrexone, 7/08 pharmacist said she ordered it in just 4 me. This wk she said has "lots" on it.
RT @PandoraFiles I'm #reading The Faces of Low Dose Naltrexone by Julia Schopick - http://bit.ly/1x3Eym
JuliaS1573 (Julia Schopick) Fri, 06 Nov 2009 23:55:55 -0000
RT @PandoraFiles I'm #reading The Faces of Low Dose Naltrexone by Julia Schopick - http://bit.ly/1x3Eym
#Naltrexone no #MS flareups for 24 yrs & no side effects
havaneese (Brian Johnson) Fri, 06 Nov 2009 20:22:50 -0000
#Naltrexone no #MS flareups for 24 yrs & no side effects

 
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