Mupirocin (pseudomonic acid A, or Bactroban) is an antibiotic originally isolated from Pseudomonas fluorescens. It is used topically, and is primarily effective against Gram-positive bacteria.

It has a unique mechanism of action, which is selective binding to bacterial isoleucyl-tRNA synthetase, which halts the incorporation of isoleucine into bacterial proteins. Because this mechanism of action is not shared with any other antibiotic, mupirocin has few problems of antibiotic cross-resistance. It is a topical treatment for bacterial skin infections, for example, furuncle, open wounds etc. It is also useful in the treatment of methicillin-resistant Staphyolococcus aureus (MRSA), which is a significant cause of death in hospitalized patients who have received systemic antibiotic therapy. It is suggested, however, that mupirocin not be used for extended periods of time, or indiscriminately, as resistance does develop, and could, if it becomes widespread, destroy mupirocin's value as a treatment for MRSA. It may also result in overgrowth of non-susceptible organisms.

The original manufacturer's (GlaxoSmithKline) product is Bactroban.

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@shitbat presciption mupirocin can help the healing. Though you had better learn to break the habit. We have some bad cases of that at work
vermyfox (Vermy Fox) Sat, 28 Jan 2012 23:52:09 -0000
@shitbat presciption mupirocin can help the healing. Though you had better learn to break the habit. We have some bad cases of that at work
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dkaoaxnyu (Muirgen Hackworthy) Sat, 28 Jan 2012 05:08:30 -0000
Mupirocin ointment discount http://t.co/cuANmz0F
Data added for mupirocin resistant isoleucyl-tRNA synthetases (mupA, mupB).
arpcard (CARD Developers) Fri, 27 Jan 2012 15:56:57 -0000
Data added for mupirocin resi Subscribe to Mupirocin RSS feed