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Modafinil (commercial trade names Provigil, Modiodal (UK, France, Mexico), Vigil (Germany), Sparlon (US), Modavigil (Australia), Alertec (Canada), and possibly Vigicer) is an eugeroic drug generally prescribed to treat narcolepsy, made by the pharmaceutical company Cephalon Inc.. It is not a typical stimulant and is often described as a "wakefulness promoting agent." It is currently under study as a treatment for depression, and it is being prescribed off-label for ADD/ADHD. In mass-media advertisments and websites, Cephalon markets the drug for improving 'alertness' and reducing 'excessive daytime sleepiness.' Cephalon has also developed and tested Nuvigil, a non-racemic version of modafinil with a longer duration of action.
Indications
Modafinil is available to treat narcolepsy, fatigue symptoms relative to Multiple Sclerosis, as well as obstructive sleep apnea/hypopnea syndrome (OSAHS), and shift work sleep disorder (SWSD). Modafinil has been shown to allow some people who suffer from excessive daytime sleepiness to remain awake without impairment of performance. In some cases modafinil produces side-effects such as headache (13% of users), nervousness (8%), nausea (5%), rashes, and intestinal problems.
The usual prescription is for a single dose to be taken shortly after waking; its effects last for most of the day without preventing normal sleep at night. The biological halflife in the human body is about 15 hours. However many patients develop a slight tolerance and report that a single dose only works well for 8 to 12 hours, and that they need to take modafinil twice a day or more. Cephalon hopes to soon release the longer-lasting Nuvigil (r-modafinil) as a "truly once-a-day" wakefulness medication. In 2006, the FDA sent Cephalon an "approvable letter" for Nuvigil, pending agreement on the final product labeling.
More on [ Modafinil ]
Narcolepsy
Stimulants :: Drugs and Medications
@TheSharkDaymond Three hours sleep? You must be munchacrunching on Modafinil!
astrochase (Matt Valentino) Thu, 07 Jan 2010 13:12:34 -0000
@TheSharkDaymond Three hours sleep? You must be munchacrunching on Modafinil!
Gebt mir mein Modafinil!!!
Kriechhund (Kriechhund) Wed, 06 Jan 2010 21:11:33 -0000
Gebt mir mein Modafinil!!!
easy to imagine being a pharma-addict. Just googled modafinil a drug dad is taking, a dream. Think adderall but more fine tuned. Learning
Carluch (Michel Carluccio) Wed, 06 Jan 2010 15:44:16 -0000
easy to imagine being a pharma-addict. Just googled modafinil a drug dad is taking, a dream. Think adderall but more fine tuned. Learning
@Osclidoo modafinil.
helennewbury (helen newbury) Wed, 06 Jan 2010 14:49:54 -0000
@Osclidoo modafinil.
Oh I'd kill for some adderall + ritalin + modafinil on this bleak morning. But coffee and coke will have to do. And not the alkaloid coke.
kch (Caio Chassot) Wed, 06 Jan 2010 09:34:03 -0000
Oh I'd kill for some adderall + ritalin + modafinil on this bleak morning. But coffee and coke will have to do. And not the alkaloid coke.
Have only just got the subtext to "Poker Face" by Lady Gaga. Sheesh. [Reaches for box of Modafinil]
FelipeAzucares (don_felipe_azucares) Tue, 05 Jan 2010 22:12:50 -0000
Have only just got the subtext to "Poker Face" by Lady Gaga. Sheesh. [Reaches for box of Modafinil]
MEDLINEplus Drug Information: Modafinil - Information sheet covering proper use, drug interactions, contraindications, and side effects.
Meta Description: [ Modafinil (Systemic) ]
Modafinil - Information from DrugDigest on dosage, usage, side effects, and interactions of this medication used to treat excessive daytime sleepiness associated with narcolepsy.
Modafinil (Provigil) - Information about this mood-brightening and memory-enhancing psychostimulant which enhances wakefulness and vigilance. Discusses mode of action and uses in treating narcolepsy, as well as experimental uses.
Meta Description: [ Modafinil is a mood-brightening and memory-enhancing psychostimulant which enhances wakefulness and vigilance. ]
Provigil - Cephalon corporate site for the company's branded version of modafinil, sold as a wake-promoting medication for treating narcolepsy. Information for U.S. patients and physicians.
Meta Description: [ Treat sleep apnea and excessive sleepiness caused by certain sleep disorders including narcolepsy, obstructive sleep apnea/hypopnea syndrome (OSAHS), and shift work sleep disorder (SWSD) ]
Provigil Consumer Information - FDA - Patient FAQ in html format with a link to approved labeling in pdf format.
RemedyFind: Patient Ratings of Provigil (Modafinil) for Depression - Site visitors post their comments on experiences with this medication as a treatment for depression.
Meta Description: [ Does Provigil etc. (Modafinil) work for Depression? Research info, studies. Patient ratings of effectiveness, side effects, cost. Share your opinion. ]
The Great Awakening: With a Pill Called Modafinil, You Can Go 40 Hours Without Sleep -- and See Into the Future - Washington Post article about the potential of this medication to change the way people live and work.
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