Minoxidil is a vasodilator and originally was exclusively used as an oral drug (Loniten®) to treat high blood pressure. It was, however, discovered to have the interesting side effect of hair growth and reversing baldness, and in the 1980s, UpJohn Corporation produced a topical solution that contained 2% minoxidil to be used to treat baldness and hair loss, under the brand name Rogaine. It is unknown how the drug stimulates hair growth.
Side effects
As a drug to combat hair loss, the most common side effect is itchy scalp.
There have been cases of allergic reactions to minoxidil or the non-active ingredient propylene glycol which is found in some forms of the topical version, such as Regaine. Large amounts of minoxidil can cause hypotension, and it has been found that using petroleum jelly or tretinoin on the scalp with minoxidil can cause too much of the drug absorption by the scalp, as can using the drug on sunburned scalps.
WL Issued to Amrex Zetron Inc FDA Tue, 14 Apr 2009 00:00:00 -0400 FDA Warning Letter Issued to Amrex Zetron Inc on 14 Apr 2009 by Los Angeles District Office WL Issued to Coast Institutional Review Board FDA Tue, 14 Apr 2009 00:00:00 -0400 FDA Warning Letter Issued to Coast Institutional Review Board on 14 Apr 2009 by Center for Drug Evaluation and Research WL Issued to Branitz, Bruce, MD FDA Thu, 09 Apr 2009 00:00:00 -0400 FDA Warning Letter Issued to Branitz, Bruce, MD on 09 Apr 2009 by Center for Drug Evaluation and Research WL Issued to Cote, Charles J., MD FDA Mon, 02 Mar 2009 00:00:00 -0400 FDA Warning Letter Issued to Cote, Charles J., MD on 02 Mar 2009 by Center for Drug Evaluation and Research WL Issued to Genzyme Corporation FDA Fri, 27 Feb 2009 00:00:00 -0400 FDA Warning Letter Issued to Genzyme Corporation on 27 Feb 2009 by New England District Office WL Issued to Hammill Manufacturing Company FDA Tue, 06 Jan 2009 00:00:00 -0400 FDA Warning Letter Issued to Hammill Manufacturing Company on 06 Jan 2009 by Cincinnati District Office
CFDA: FDA Latest Drug GCP Warning Letters
WL Issued to Coast Institutional Review Board FDA Tue, 14 Apr 2009 00:00:00 -0400 FDA Warning Letter Issued to Coast Institutional Review Board on 14 Apr 2009 by Center for Drug Evaluation and Research WL Issued to Branitz, Bruce, MD FDA Thu, 09 Apr 2009 00:00:00 -0400 FDA Warning Letter Issued to Branitz, Bruce, MD on 09 Apr 2009 by Center for Drug Evaluation and Research WL Issued to Bukowski, Ronald M, MD FDA Mon, 30 Mar 2009 00:00:00 -0400 FDA Warning Letter Issued to Bukowski, Ronald M, MD on 30 Mar 2009 by Center for Drug Evaluation and Research WL Issued to Youabian, Inc FDA Tue, 17 Mar 2009 00:00:00 -0400 FDA Warning Letter Issued to Youabian, Inc on 17 Mar 2009 by Los Angeles District Office WL Issued to Provena St. Joseph's Medical Center IRB FDA Thu, 12 Mar 2009 00:00:00 -0400 FDA Warning Letter Issued to Provena St. Joseph's Medical Center IRB on 12 Mar 2009 by Center for Biologics Evaluation and Research WL Issued to Paulson, Daniel M., MD FDA Wed, 11 Mar 2009 00:00:00 -0400 FDA Warning Letter Issued to Paulson, Daniel M., MD on 11 Mar 2009 by Center for Drug Evaluation and Research
DrugDigest: Minoxidil ( Loniten ) - Information on dosage, usage, side effects, interactions, and drug comparisons, including generics when available.
Rogaine.com - Manufacturer's site about a treatment solution, with FAQ and a forum.
Meta Description: [ Rogaine works, the sooner the better. In 1998, Rogaine became the first FDA-approved treatment for hair regrowth. Use this page to select either the Men's Rogaine site, the Rogaine for Women site, or a site to purchase Rogaine online. ]
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