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Miconazole is an imidazole antifungal agent commonly applied topically (to the skin) or mucus membranes to cure fungal infections. It works by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes. It can also be used against certain species of Leishmania protozoa (which are a type of unicellular parasite), as these also contain ergosterol in their cell membranes. In addition to its antifungal and antiparasitic actions, it also has some limited antibacterial properties.
Indications
Miconazole is mainly used externally for the treatment of Athlete's foot, Ringworm and Jock itch. Internal application is used for oral or vaginal thrush (yeast infection). It has an advantage over nystatin in the treatment of neonatal oral thrush in that the latter is only licensed in the UK for those over the age of one month; but note the possibility for drug interactions.
Side effects
Unlike nystatin, some miconazole is absorbed by the intestinal tract when used orally (and possibly if used vaginally ) which may lead to drug interactions. More on [ Miconazole ]
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DrugDigest: Miconazole - Information on dosage, usage, side effects, interactions, and drug comparisons, including generics when available. Sold under brand names such as: Breezee Mist, Desenex, Fungoid Tincture, Micatin, Monistat-Derm, Ony-Clear, Tetterine, Zeasorb.
DrugDigest: Miconazole Vaginal Suppository - Information on dosage, usage, side effects, interactions, and drug comparisons incl,uding generics when available. Sold under brand names such as Femizol-M and Monistat.
Monistat - Miconazole nitrate. Provides product information and savings coupon for Canadian consumers as well as yeast infection information, FAQs, and interactive features.
Monistat - Miconazole nitrate. Features product information for US consumers as well as yeast infection FAQs and information.
