Metronidazole (INN) (IPA: ) is a nitroimidazole anti-infective drug used mainly in the treatment of infections caused by susceptible organisms, particularly anaerobic bacteria and protozoa. It is marketed by Sanofi-Aventis under the trade name Flagyl, and also by various generic manufacturers. Metronidazole is also used in the treament of the dermatological condition rosacea, where it is marketed by Galderma under the trade names Rozex and MetroGel.

Mode of action

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Metronidazole is selectively taken up by anaerobic bacteria and sensitive protozoal organisms because of the ability of these organisms to reduce metronidazole to its active form intracellularly. The nitro group of metronidazole is chemically reduced by ferredoxin (or ferredoxin-linked metabolic process) and the products are responsible for disrupting the DNA helical structure, thus inhibiting nucleic acid synthesis.

Indications

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Systemic metronidazole is indicated for the treatment of:

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just looking up the risks of drinking while taking metronidazole antibiotics.. the jury is out.. wine time !!!
craigyknit (craig kniter) Sun, 08 Nov 2009 13:18:27 -0000
just looking up the risks of drinking while taking metronidazole antibiotics.. the jury is out.. wine time !!!
..then treatments: metronidazole (Flagyl), then Drontal Plus, then fenbendazole (Panacur). Nothing worked and they were all unpleasant..
samadamsthedog (sam adams the dog) Sat, 07 Nov 2009 22:07:32 -0000
..then treatments: metronidazole (Flagyl), then Drontal Plus, then fenbendazole (Panacur). Nothing worked and they were all unpleasant..
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(metronidazole and special food for Monte. The food's going to be a bitch.)
Wecanhaztweets (Jon's kittehs!) Fri, 06 Nov 2009 21:01:03 -0000
(metronidazole and special food for Monte. The food's going to be a bitch.)
last job of the shift was a 11 year old having quite an adverse reaction to metronidazole. He collapsed and wasn't really with it at all.
fu11er (Michael) Fri, 06 Nov 2009 19:19:40 -0000
last job of the shift was a 11 year old having quite an adverse reaction to metronidazole. He collapsed and wasn't really with it at all.
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