Methadone is a synthetic opioid, used medically as an analgesic and in the treatment of narcotic addiction.

History

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Methadone was first synthesized in 1937 by German scientists Max Bockmühl and Gustav Ehrhart at IG Farben (Hoechst-Am-Main) during their search for an analgesic that would be easier to use during surgery and also have low addiction potential. Methadone is a Schedule II drug under the Single Convention on Narcotic Drugs^*.

On September 11, 1941 Bockmühl and Ehrhart filed an application for a patent for a synthetic substance they called Hoechst 10820 or polamidon and whose structure had no relation to morphine or the opioid alkaloids (Bockmühl and Ehrhart, 1949). Although chemically unlike morphine or heroin, methadone also acts on the opioid receptors and thus produces many of the same effects. Chemically, methadone is the simplest of the opioids.

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@maljunaibi the treatment at this time wasn't based on substitution by other medicine like methadone and subutex which is the case in Eur
mahamiou (Maha) Sun, 29 Jan 2012 14:35:22 -0000
@maljunaibi the treatment at this time wasn't based on substitution by other medicine like methadone and subutex which is the case in Eur
@_Mateh S8s are schedule 8s, or controlled drugs, including things like codeine (pure), morphine, methadone, hydromorphone, oxycodone, etc.
ViciousPotato (Cameron Grant) Sun, 29 Jan 2012 14:30:26 -0000
@_Mateh S8s are schedule 8s, or controlled drugs, including things like codeine (pure), morphine, methadone, hydromorphone, oxycodone, etc.
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