Gourt > Health > Pharmacy > Drugs and Medications > M > Melphalan
Melphalan hydrochloride ( Alkeran®) is a chemotherapy drug belonging to the class of nitrogen mustard alkylating agents. It is used primarily to treat multiple myeloma and ovarian cancer, and occasionally malignant melanoma. Otherwise known as L-Phenylalanine Mustard, or L-PAM, melphalan is a phenylalanine derivative of mechlorethamine. The agent was first investigated as a possible drug for use in melanoma. It did not work, but was found to be of use in myeloma.
Administration
Oral or intravenous; dosing varies by purpose and route of administration as well as patient weight.
Side effects
Common side effects include:
- Nausea and vomiting
- Bone marrow suppression, including
- Decreased white blood cell count causing increased risk of infection
- Decreased platelet count causing increased risk of bleeding
Allergy/Immunology Increased Plasma-Immune Cytokines throughout the High-Dose Melphalan-Induc.. http://bit.ly/4peUhh
MDLinx (Sandeep Pulim MD) Thu, 07 Jan 2010 13:17:36 -0000
Allergy/Immunology Increased Plasma-Immune Cytokines throughout the High-Dose Melphalan-Induc.. http://bit.ly/4peUhh
Increased Plasma-Immune Cytokines throughout the High-Dose Melphalan-Induced Lymphodepletion in Patients with M.. http://bit.ly/7pHNwz
cytokine (BioPortfolio) Thu, 07 Jan 2010 12:15:54 -0000
Increased Plasma-Immune Cytokines throughout the High-Dose Melphalan-Induced Lymphodepletion in Patients with M.. http://bit.ly/7pHNwz
RT @myelomatrials RT @_clinical_trial melphalan, prednisone, & thalidomide or lenalidomide in treating ppl w/ newly diagnosed ...
myelomatrials (Myeloma Trials) Sat, 02 Jan 2010 22:21:03 -0000
RT @myelomatrials RT @_clinical_trial melphalan, prednisone, & thalidomide or lenalidomide in treating ppl w/ newly diagnosed ...
RT @_clinical_trial melphalan, prednisone, & thalidomide or lenalidomide in treating ppl w/ newly diagnosed multiple myeloma h...
myelomatrials (Myeloma Trials) Sat, 02 Jan 2010 21:21:05 -0000
RT @_clinical_trial melphalan, prednisone, & thalidomide or lenalidomide in treating ppl w/ newly diagnosed multiple myeloma h...
RT @myelomatrials RT @goclinicaltrial melphalan, prednisone, & thalidomide or lenalidomide in treating ppl w/ newly diagnosed ...
myelomatrials (Myeloma Trials) Sat, 02 Jan 2010 20:21:05 -0000
RT @myelomatrials RT @goclinicaltrial melphalan, prednisone, & thalidomide or lenalidomide in treating ppl w/ newly diagnosed ...
RT @goclinicaltrial melphalan, prednisone, & thalidomide or lenalidomide in treating ppl w/ newly diagnosed multiple myeloma h...
myelomatrials (Myeloma Trials) Sat, 02 Jan 2010 19:21:04 -0000
RT @goclinicaltrial melphalan, prednisone, & thalidomide or lenalidomide in treating ppl w/ newly diagnosed multiple myeloma h...
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Alkeran - Tablets and injection. Prescribing information for US residents in PDF format. [Acrobat Reader required]
Meta Description: [ About GSK summarizes the mission of GSK and provides users with an overview of the organization and biographies of our Board of Directors and Corporate Executive Team. ]
Alkeran - Product information from Glaxo Wellcome, in Portable Document Format (PDF). (melphalan)
Meta Description: [ This site serves as the homepage of GSK's corporate web site. ]
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Alkeran - Prescribing information for UK residents in PDF format. [Acrobat Reader required]
Meta Description: [ About GSK summarizes the mission of GSK and provides users with an overview of the organization and biographies of our Board of Directors and Corporate Executive Team. ]
DrugDigest: Melphalan ( Alkeran, L-PAM ) - Information on dosage, usage, side effects, interactions, and drug comparisons including generics when available.
MEDLINEplus: Melphalan - Features information about dosage, usage, side effects, and warnings.
Meta Description: [ Melphalan (Systemic) ]
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