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Lidocaine (INN) (IPA: ) or lignocaine (former BAN) (IPA: ) is a common local anesthetic and antiarrhythmic drug. The most commonly encountered lidocaine preparations are marketed by AstraZeneca under the brand names Xylocaine and Xylocard, though lidocaine is also found in many other proprietary preparations.

History


Lidocaine, the first amino amide-type local anesthetic, was developed by Nils Löfgren and Bengt Lundqvist in 1943 and first marketed in 1948.

Pharmacokinetics


Lidocaine has a more rapid onset of action and longer duration of action than amino ester-type local anesthetics such as procaine. It is approximately 90% metabolized in the liver by CYP1A2 (and to a minor extent CYP3A4) to the pharmacologically-active metabolites monoethylglycinexylidide and glycinexylidide.

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@smizzarr All nighter with me? >_>
lidocaine (Riddick 天津甕星) Fri, 11 Dec 2009 05:57:41 -0000
@smizzarr All nighter with me? >_>
RT @crackberry: BlackBerry App Roundup for December 11th, 2009! http://bit.ly/6kGcfA
lidocaine (Riddick 天津甕星) Fri, 11 Dec 2009 05:36:44 -0000
RT @crackberry: BlackBerry App Roundup for December 11th, 2009! http://bit.ly/6kGcfA
RT @DonCortez: @ClaudeKelly *sings to the cheesy 90s production* Ghostwriter~~~ WORD!
lidocaine (Riddick 天津甕星) Fri, 11 Dec 2009 05:33:43 -0000
RT @DonCortez: @ClaudeKelly *sings to the cheesy 90s production* Ghostwriter~~~ WORD!
@ProfessorZenith Why the lidocaine, anyway?
shadowmaat (Shadow of Ma'at) Fri, 11 Dec 2009 05:12:52 -0000
@ProfessorZenith Why the lidocaine, anyway?
Why every time I think of Santana, I picture an old Mexican corpse (dressed like a cheap matador, of course) playing the guitar?
lidocaine (Riddick 天津甕星) Fri, 11 Dec 2009 04:19:58 -0000
Why every time I think of Santana, I picture an old Mexican corpse (dressed like a cheap matador, of course) playing the guitar?
Libel is written. Slander is spoken. Fuck you. #StayInSchool
lidocaine (Riddick 天津甕星) Fri, 11 Dec 2009 04:13:14 -0000
Libel is written. Slander is spoken. Fuck you. #StayInSchool

 
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DrugDigest: Lidocaine Viscous ( Xylocaine ) - Information on dosage, usage, side effects, interactions, and drug comparisons, including generics when available.

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