Lidocaine (INN) (IPA: ) or lignocaine (former BAN) (IPA: ) is a common local anesthetic and antiarrhythmic drug. The most commonly encountered lidocaine preparations are marketed by AstraZeneca under the brand names Xylocaine and Xylocard, though lidocaine is also found in many other proprietary preparations.

History

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Lidocaine, the first amino amide-type local anesthetic, was developed by Nils Löfgren and Bengt Lundqvist in 1943 and first marketed in 1948.

Pharmacokinetics

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Lidocaine has a more rapid onset of action and longer duration of action than amino ester-type local anesthetics such as procaine. It is approximately 90% metabolized in the liver by CYP1A2 (and to a minor extent CYP3A4) to the pharmacologically-active metabolites monoethylglycinexylidide and glycinexylidide.

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RT @JustPlainT: Vanek upper body injury = titty twister. Lidocaine and a bra. #nuffsaid #Sabres
whitey26515 (Sean White) Fri, 23 Dec 2011 02:57:07 -0000
RT @JustPlainT: Vanek upper body injury = titty twister. Lidocaine and a bra. #nuffsaid #Sabres
@xrossfade42 not at all unless you mind the injections of lidocaine :) I was completely numb. #thankgod
_mybrokensmile_ (Lynne C) Fri, 23 Dec 2011 02:45:30 -0000
@xrossfade42 not at all unless you mind the injections of lidocaine :) I was completely numb. #thankgod
+1 RT@JustPlainT Vanek upper body injury = titty twister. Lidocaine and a bra. #nuffsaid #Sabres
RavenLurks (Donna) Fri, 23 Dec 2011 02:20:46 -0000
+1 RT@JustPlainT Vanek upper body injury = titty twister. Lidocaine and a bra. #nuffsaid #Sabres
Vanek upper body injury = titty twister. Lidocaine and a bra. #nuffsaid #Sabres
JustPlainT (Just Plain T) Fri, 23 Dec 2011 02:18:55 -0000
Vanek upper body injury = titty twister. Lidocaine and a bra. #nuffsaid #Sabres
@BlondeByDesign Still fighting body pain, especially spine radiating down my hips & legs. Lidocaine patches help with relief quite a bit.
SashaKane (SashaKane) Fri, 23 Dec 2011 01:55:41 -0000
@BlondeByDesign Still fighting body pain, especially spine radiating down my hips & legs. Lidocaine patches help with relief quite a bit.
@moomo_ yuk. Tp aku ngak pernah lg stalking, membunuh kita itu. mereka enk2an twit pcran kitanya nangis darah. *suntik lidocaine di hati*
rezhent (Kusuma) Fri, 23 Dec 2011 01:19:57 -0000
@moomo_ yuk. Tp aku ngak pernah lg stalking, membunuh kita itu. mereka enk2an twit pcran kitanya nangis darah. *suntik lidocaine di hati*

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