CAS number	ATC code
Chemical formula
Molecular weight
Bioavailability
Metabolism
Elimination half-life
Excretion
Pregnancy category	C
Legal status	USA: Schedule II
Routes of administration	Oral (Capsules), Subcutaneous, Intramuscular, Intravenous

Levorphanol is an opioid medication used to treat severe pain. The medication has an abuse potential. In addition to acting on opioid receptors, it also acts on NMDA receptors. Typical doses include 2 mg by mouth or subcutaneous injection every 6 to 8 hours.

It is related to dextromethorphan, an antitussive which is not an opiate. Dextromethorphan is a salt of the methyl ether dextrorotatory isomer of levorphanol. Dextromethorphan is an opioid, but it is available without prescription because one has to overdose on it to feel its effects. Another common drug which is a synthetic opiate is loperamide HCl, otherwise known as Immodium A-D. It is similar to DXM because it treads on a side effect of a very weak synthetic opiate.

More on [ Levorphanol ]

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FDA Thu, 09 Apr 2009 00:00:00 -0400
FDA Warning Letter Issued to Branitz, Bruce, MD on 09 Apr 2009 by Center for Drug Evaluation and Research
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FDA Warning Letter Issued to Cote, Charles J., MD on 02 Mar 2009 by Center for Drug Evaluation and Research
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FDA Warning Letter Issued to Genzyme Corporation on 27 Feb 2009 by New England District Office
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FDA Tue, 06 Jan 2009 00:00:00 -0400
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CFDA: FDA Latest Drug GCP Warning Letters

WL Issued to Coast Institutional Review Board
FDA Tue, 14 Apr 2009 00:00:00 -0400
FDA Warning Letter Issued to Coast Institutional Review Board on 14 Apr 2009 by Center for Drug Evaluation and Research
WL Issued to Branitz, Bruce, MD
FDA Thu, 09 Apr 2009 00:00:00 -0400
FDA Warning Letter Issued to Branitz, Bruce, MD on 09 Apr 2009 by Center for Drug Evaluation and Research
WL Issued to Bukowski, Ronald M, MD
FDA Mon, 30 Mar 2009 00:00:00 -0400
FDA Warning Letter Issued to Bukowski, Ronald M, MD on 30 Mar 2009 by Center for Drug Evaluation and Research
WL Issued to Youabian, Inc
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FDA Warning Letter Issued to Youabian, Inc on 17 Mar 2009 by Los Angeles District Office
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FDA Warning Letter Issued to Provena St. Joseph's Medical Center IRB on 12 Mar 2009 by Center for Biologics Evaluation and Research
WL Issued to Paulson, Daniel M., MD
FDA Wed, 11 Mar 2009 00:00:00 -0400
FDA Warning Letter Issued to Paulson, Daniel M., MD on 11 Mar 2009 by Center for Drug Evaluation and Research

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