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Leuprolide/Leuprorelin is a gonadotropin-releasing hormone agonist (GnRH agonist). By causing constant stimulation of the pituitary GnRH receptors, it initially causes stimulation (flare), but thereafter decreases pituitary secretion (downregulation) of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH). Like other GnRH agonists, leuprolide may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, estrogen-dependent conditions (such as endometriosis or uterine fibroids), to treat precocious puberty, and to control ovarian stimulation in IVF.

Leuprolide acetate is marketed by Bayer AG under the brand name Viadur, by Sanofi-Aventis under the brand name Eligard, and by TAP Pharmaceuticals under the brand name Lupron. It is available as a slow-release implant or sub-cutaneous/intramuscular injection.

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RT @Transplant_Doc: Leuprolide failed to preserve ovarian function in patients who underwent allogeneic transplants: MD Anderson Study http://t.co/lSUXUO1k
Myeloma_Doc (Robert Z. Orlowski) Sun, 29 Jan 2012 15:09:26 -0000
RT @Transplant_Doc: Leuprolide failed to preserve ovarian function in patients who underwent allogeneic transplants: MD Anderson Study http://t.co/lSUXUO1k
RT @fischmd: Bummer: RT @transplant_doc: Leuprolide failed to preserve ovarian function in allogeneic transplant pts,http://t.co/aCznMXUe, #fertility
mtmdphd (Mike Thompson, MDPhD) Sat, 28 Jan 2012 21:57:24 -0000
RT @fischmd: Bummer: RT @transplant_doc: Leuprolide failed to preserve ovarian function in allogeneic transplant pts,http://t.co/aCznMXUe, #fertility
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Leuprolide acetate - Familydoctor.org - Information for patients in English and Spanish.

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