submit urlsubmit rss feedadd directoryphysician directoryPharmacology opportunity

article

Folinic acid (INN) or leucovorin (USAN), generally administered as calcium folinate (or leucovorin calcium), is an adjuvant used in cancer chemotherapy involving the drug methotrexate. It is also used in synergistic combination with the chemotherapy 5-fluorouracil.

Folinic acid is not folic acid.

Mechanism of action


Folinic acid is a 5-formyl-derivative of tetrahydrofolic acid. It is readily converted to other reduced folic acid derivatives (e.g. tetrahydrofolate). Since it does not require the action of dihydrofolate reductase for its conversion, it will be unaffected by inhibition of this enzyme by drugs such as methotrexate.

More on [ Folinic acid ]


directory of related categories

 
Leucovorin RSS feed
Leucovorin - Twitter Search

Oxaliplatin & Leucovorin infusing.. now starts chemo-session #2..
melsocal (melsocal) Thu, 05 Nov 2009 18:40:29 -0000
Oxaliplatin & Leucovorin infusing.. now starts chemo-session #2..

 
Subscribe to Leucovorin RSS feed

directory of related sites

Leucovorin - The active form of the B complex vitamin, folate.(Citrovorum, Wellcovorin, folinic acid)

Leucovorin - Familydoctor.org - Information for patients in English and Spanish.

Leucovorin related videos
Is It A Good Idea To Microwave A Robosapien?
Next Video
Leucovorin related videos

 

HOMEADVERTISINGABOUT US

articlesartsbusinesscomputersgameshealthhospitalshomekids & teensnewsmobilephysiciansrecreationreferenceregionalscienceshoppingsocietysportsworld


Submit a Site About Become an Editor