Letrozole (Femara®) is an oral non-steroidal aromatase inhibitor that has been introduced for the adjuvant treatment of hormonally-responsive breast cancer.
Estrogens are produced by the conversion of androgens through the activity of the aromatase enzyme. Letrozole blocks production of estrogens in this way by competitive, reversible binding to the heme of its cytochrome p450 unit. The action is specific, and letrozole does not reduce production of mineralo- or corticosteroids. In contrast, the antiestrogenic action of Tamoxifen, the major medical therapy prior to the arrival of aromatase inhibitors, is due to its interfering with the estrogen receptor, rather than inhibiting estrogen production.
FDA-approved use
Letrozole is approved by the
Food and Drug Administration (FDA) for the treatment of local or metastatic breast cancer that is hormone receptor positive or has an unknown receptor status in postmenopausal women.
Side effects include signs and symptoms of
hypoestrogenism. There is concern that long term use may lead to
osteoporosis.
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Letrozole - Twitter Searchhas no chance , letrozole even told me that ..cristianflowers (cristian flowers ) Fri, 06 Nov 2009 22:20:39 -0000
has no chance , letrozole even told me that ..
Fucking lexi and her outbursts ! letrozole sooo heard what she said about the sex thing ! :$cristianflowers (cristian flowers ) Thu, 05 Nov 2009 22:31:44 -0000
Fucking lexi and her outbursts ! letrozole sooo heard what she said about the sex thing ! :$
He soo likes mariah creighton . duuuumbass :P , im like all gaga over letrozole again :\ grr to my stupiditycristianflowers (cristian flowers ) Thu, 05 Nov 2009 18:02:10 -0000
He soo likes mariah creighton . duuuumbass :P , im like all gaga over letrozole again :\ grr to my stupidity
This new protocol with a little letrozole should burn a butt load of fat in combination with a diet of meat and veggies.Bionixx (THE DONSTER ) Wed, 04 Nov 2009 19:12:01 -0000
This new protocol with a little letrozole should burn a butt load of fat in combination with a diet of meat and veggies.
And of course on this shitty day the first person i see as i turn the corner to my locker is Letrozole :(cristianflowers (cristian flowers ) Wed, 04 Nov 2009 15:08:10 -0000
And of course on this shitty day the first person i see as i turn the corner to my locker is Letrozole :(
master plan of taking bus failed . letrozole got picked up :( am i really that shit?cristianflowers (cristian flowers ) Tue, 03 Nov 2009 23:47:16 -0000
master plan of taking bus failed . letrozole got picked up :( am i really that shit?
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DrugDigest: Letrozole ( Femara ) - Information on dosage, usage, side effects, interactions, and drug comparisons including generics when available.
Femara - Product information for US residents and health care professionals.
Meta Description: [ Breast Cancer FEMARA - post-tamoxifen treatment for post menopausal women with early stage breast cancer ]
Femara ( Letrozole ) - Offers patient and prescribing information from the manufacturer.
Meta Description: [ Novartis Pharmaceuticals Canada Inc. - Our Products - Femara ]
Femara International - Official international pharmaceutical website with information for patients and health professionals.
Meta Description: [ Femara is indicated for the treatment of early breast cancer in postmenopausal women who have completed prior standard tamoxifen therapy. On Femarainfo.com Novartis Oncology provides international healthcare professionals with patient case studies and education materials as well as information on... ]