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Lamivudine (2',3'-dideoxy-3'-thiacytidine, 3TC) is a potent reverse transcriptase inhibitor of the class nucleoside analog reverse transcriptase inhibitor (NARTI).
It is marketed by GlaxoSmithKline with the brand names Epivir® and Epivir-HBV®. It is also called 3TC
Lamivudine has been used for treatment of chronic hepatitis B at a lower dose than for treatment of HIV. It improves the seroconversion of e-antigen positive hepatitis B and also improves histology staging of the liver. Long term use of lamivudine unfortunately leads to emergence of a resistant hepatitis B virus (YMDD) mutant. Despite this, lamivudine is still used widely as it is well tolerated.
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Combivir - Lamivudine and zidovudine. Features product and prescribing information for US consumers and healthcare professionals.
DrugDigest: Lamivudine - Information on dosage, usage, side effects, interactions, and drug comparisons, including generics when available. Sold under brand names such as: 3TC, Epivir, and Epivir-HBV.
Epivir - Product information for US residents in PDF format. [Acrobat Reader required]
Epivir HBV - Product information for US residents in PDF format. [Acrobat Reader required]
Lamivudine - a.k.a. 3TC, Epivir.
Lamivudine - (Epivir, 3TC)
Meta Description: [ lamivudine, 3TC (Epivir) ]
Lamivudine (3TC) - An antiretroviral (anti-HIV) agent, which belongs to a class of drugs called nucleoside analogue reverse transcriptase inhibitors.
Lamivudine - Familydoctor.org - Information for patients in English and Spanish.
Lamivudine and Zidovudine ( Combivir ) - Manufacturer's publication on this nucleoside reverse transcriptase inhibitor for the treatment of HIV.
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Zeffix UK - GlaxoSmithKline prescribing information for UK residents.
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