For the collaborative acoustic project, see Katamine.

Ketamine is a general dissociative anaesthetic for human and veterinary use. Its hydrochloride salt is sold as Ketanest®, Ketaset®, and Ketalar®. Pharmacologically it is very similar to other dissociative anesthetics such as tiletamine and phencyclidine (PCP).

History

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Ketamine was first synthesized in 1962 in an attempt to find a safer anaesthetic alternative to PCP, which was more likely to cause hallucinations and seizures. The drug was first used on American soldiers during the Vietnam War, but is often avoided now because it can cause potentially unpleasant out-of-body experiences. It is still used widely in veterinary medicine, and for select human applications.

Ketamine's "unpleasant" side effects eventually made it a popular psychedelic in 1965. The drug was used in psychiatric and other academic research through the 1970s, culminating in 1978 with the publishing of John Lilly's The Scientist, a book documenting the author's ketamine, LSD, and isolation tank experiments. The incidence of recreational ketamine use increased through the end of the century, especially in the context of raves and other parties. The increase in illicit use prompted ketamine's placement in Schedule III of the United States Controlled Substance Act in August 1999. In the United Kingdom, it became outlawed and labelled a Class C drug on January 1, 2006.^*

More on [ Ketamine ]

CFDA: FDA Latest Computer Systems Warning Letters

WL Issued to Oncology Tech, LLP
FDA Fri, 27 Jun 2008 00:00:00 -0400
FDA Warning Letter Issued to Oncology Tech, LLP on 27 Jun 2008 by Dallas District Office
WL Issued to Mostel, Edward, M.D.
FDA Fri, 16 May 2008 00:00:00 -0400
FDA Warning Letter Issued to Mostel, Edward, M.D. on 16 May 2008 by Center for Drug Evaluation and Research
WL Issued to Merck & Company, Inc.
FDA Mon, 28 Apr 2008 00:00:00 -0400
FDA Warning Letter Issued to Merck & Company, Inc. on 28 Apr 2008 by Office of Enforcement
WL Issued to Blood Center of New Jersey
FDA Tue, 15 Apr 2008 00:00:00 -0400
FDA Warning Letter Issued to Blood Center of New Jersey on 15 Apr 2008 by New Jersey District Office
WL Issued to Asfora, Wilson T. M.D.
FDA Mon, 07 Apr 2008 00:00:00 -0400
FDA Warning Letter Issued to Asfora, Wilson T. M.D. on 07 Apr 2008 by Center for Devices and Radiological Health
WL Issued to Philips Medical Systems, Inc
FDA Tue, 01 Apr 2008 00:00:00 -0400
FDA Warning Letter Issued to Philips Medical Systems, Inc on 01 Apr 2008 by Cincinnati District Office

CFDA: FDA Latest Drug GCP Warning Letters

WL Issued to Gardiziola, Gregory, D.O.
FDA Wed, 03 Sep 2008 00:00:00 -0400
FDA Warning Letter Issued to Gardiziola, Gregory, D.O. on 03 Sep 2008 by Center for Drug Evaluation and Research
WL Issued to Hamilton Medical Center
FDA Tue, 02 Sep 2008 00:00:00 -0400
FDA Warning Letter Issued to Hamilton Medical Center on 02 Sep 2008 by Center for Devices and Radiological Health
WL Issued to Ziran, Bruce H., MD
FDA Wed, 27 Aug 2008 00:00:00 -0400
FDA Warning Letter Issued to Ziran, Bruce H., MD on 27 Aug 2008 by Center for Devices and Radiological Health
WL Issued to Hospital Municipal de San Juan
FDA Fri, 15 Aug 2008 00:00:00 -0400
FDA Warning Letter Issued to Hospital Municipal de San Juan on 15 Aug 2008 by Center for Drug Evaluation and Research
WL Issued to Valley Baptist Medical Center IRB
FDA Mon, 11 Aug 2008 00:00:00 -0400
FDA Warning Letter Issued to Valley Baptist Medical Center IRB on 11 Aug 2008 by Center for Devices and Radiological Health
WL Issued to Husain, Mustafa M, M.D.
FDA Wed, 23 Jul 2008 00:00:00 -0400
FDA Warning Letter Issued to Husain, Mustafa M, M.D. on 23 Jul 2008 by Center for Devices and Radiological Health

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