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Itraconazole (marketed as Sporanox® by Janssen Pharmaceutica) is a triazole antifungal agent that is prescribed to patients with fungal infections. The drug may be given orally or intravenously.
Pharmacology
The mechanism of action of itraconazole is the same as the other azole antifungals: it inhibits cytochrome P450 oxidase mediated synthesis of ergosterol.
Indication
Itraconazole has a broader spectrum of activity than fluconazole (but not as broad as voriconazole or posaconazole). In particular, it is active against aspergillus, which fluconazole is not. It is also licenced for use in blastomycosis, histoplasmosis and onychomycosis. More on [ Itraconazole ]
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DrugDigest: Itraconazole ( Sporanox ) - Information on dosage, usage, side effects, interactions, and drug comparisons, including generics when available.
Itraconazole (Sporonox) - Dosage, side effects and other topics related to the use of this medication for HIV-related conditions.
Itraconazole (Sporonox) - Information about this antifungal medication commonly used in treating HIV and AIDS. Includes dosage, side effects, contraindications, and drug interactions.
Itraconozole (oral) - Basic information about this antifungal agent.
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