Gourt > Health > Pharmacy > Drugs and Medications > I > Isoniazid
.png | CAS_number = 54-85-3 | ATC_prefix = J04 | ATC_suffix = AC01 | ATC_supplemental = | PubChem = 3767 | DrugBank = APRD01055 | chemical_formula = C6H7N3O | molecular_weight = 137.139 g/mol | bioavailability = | protein_bound = Very low (0-10%) | metabolism = | elimination_half-life = | pregnancy_category = | legal_status = | routes_of_administration = }} Isoniazid (also called isonicotinyl hydrazine or isonicotinic acid hydrazide); abbreviated INH or just H. Isoniazid is a first-line antituberculous medication used in the prevention and treatment of tuberculosis.
It is available in tablet, syrup, and injectable forms (given via intramuscular or intravenous forms), available world-wide, inexpensive to produce and is generally well tolerated.
Mechanism of action
Isoniazid is a prodrug and must be activated by bacterial catalase. The active form inhibits the synthesis of mycolic acid in the mycobacterial cell wall. More on [ Isoniazid ]
DrugDigest: Isoniazid - Information on dosage, usage, side effects, interactions, and drug comparisons, including generics when available. Sold under brand names such as: INH, Laniazid, and Nydrazid.
Isoniazid - Basic information about this antimycobacterial.
Isoniazid - (INH, Lanizid, Nydrazid)
