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Infliximab (Remicade®) is a powerful drug used to treat auto-immune disorders like Crohn's disease and rheumatoid arthritis. Infliximab is known as a "chimeric monoclonal antibody" (the term "chimeric" refers to the use of both mouse and human components of the drug i.e. mouse binding VK and VH domains and human constant Fc domains). The drug reduces the amount of active TNF-α (tumour necrosis factor alpha) in the body by binding to it and preventing it from signaling the receptors for TNF-α on the surface of cells. TNF-α is one of the key cytokines that triggers and sustains the inflammation response. Remicade was invented by Junming Le and Jan Vilcek at New York University School of Medicine and developed by Centocor, a pharmaceutical company owned by Johnson & Johnson.
In the United States, Infliximab is indicated (approved by the US Food and Drug Administration (FDA)) for the treatment of rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, ulcerative colitis, adult Crohn's disease and pediatric Crohn's disease. It is the only anti-TNF alpha biologic in its class with an indication for the latter 3 diseases.
Remicade is administered by intravenous infusion, typically at a clinic or hospital. It cannot be administered orally, because the digestive system would destroy the drug.
More on [ Infliximab ]
Crohn's Disease
Rheumatoid Arthritis
Efficacy of Infliximab treatment in patients with severe Fistulizing Hidradenitis Suppurativa http://tinyurl.com/ycq62qb
hssupport (HS Support) Thu, 05 Nov 2009 12:43:39 -0000
Efficacy of Infliximab treatment in patients with severe Fistulizing Hidradenitis Suppurativa http://tinyurl.com/ycq62qb
Int Med: The relationship between synovial lymphocyte aggregates and the clinical response to infliximab in rheumatoid a http://url4.eu/hDGQ
MDLinx (Sandeep Pulim MD) Wed, 04 Nov 2009 12:40:00 -0000
Int Med: The relationship between synovial lymphocyte aggregates and the clinical response to infliximab in rheumatoid a http://url4.eu/hDGQ
Rheum: Treatment of early RA with infliximab is beneficial: American Pharmacists Association http://url4.eu/hClL
MDLinx (Sandeep Pulim MD) Wed, 04 Nov 2009 09:26:26 -0000
Rheum: Treatment of early RA with infliximab is beneficial: American Pharmacists Association http://url4.eu/hClL
Rheum: The relationship between synovial lymphocyte aggregates and the clinical response to infliximab in rheumatoid art http://url4.eu/hClJ
MDLinx (Sandeep Pulim MD) Wed, 04 Nov 2009 09:26:26 -0000
Rheum: The relationship between synovial lymphocyte aggregates and the clinical response to infliximab in rheumatoid art http://url4.eu/hClJ
Call of duty:: Re: Demand Infliximab?: Hi you should be able to have infliximab as my son Adam is 11yrs old he .. http://bit.ly/3g0Nbt
ColitisUK (Colitis UK) Wed, 04 Nov 2009 07:18:21 -0000
Call of duty:: Re: Demand Infliximab?: Hi you should be able to have infliximab as my son Adam is 11yrs old he .. http://bit.ly/3g0Nbt
algumas drogas parecem ter sido batizadas por george lucas: anakinra, abatacept, rituximab, etanercept, infliximab, adalimumab, abciximab...
tat_can (tatiane cantarelli) Wed, 04 Nov 2009 00:48:34 -0000
algumas drogas parecem ter sido batizadas por george lucas: anakinra, abatacept, rituximab, etanercept, infliximab, adalimumab, abciximab...
DrugDigest: Infliximab (Remicade) - Information on dosage, usage, side effects, interactions, and drug comparisons, including generics when available.
Remicade - Details about this drug treatment for Crohn's Disease and rheumatoid arthritis, by Centocor Pharmaceuticals.
The Remicade Letters - CBC: Disclosure - A look at a controversial marketing campaign and the drug company behind it.
Meta Description: [ A look at a controversial marketing campaign and the drug company behind it. ]
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