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Imipramine (sold as Antideprin®, Janimine®, Tofranil®) is an antidepressant medication, a tricyclic antidepressant of the dibenzazepine group, mainly used in the treatment of clinical depression and enuresis.
Imipramine was, in the late 1950s, the first tricyclic antidepressant to be developed (by Ciba-Geigy). Initially, it was tried against psychotic disorders (e.g. schizophrenia), but proved insufficient. During the clinical studies its antidepressant qualities, unsurpassed until today, became evident. Subsequently it was extensively used as standard antidepressant and later served as a prototypical drug for the development of the later released tricyclics. It is not as commonly used today but sometimes used to treat major depression as a second-line treatment. It has also seen limited use in the treatment of migraines, ADD and post concussive syndrome. Imipramine has additional indications for the treatment of panic attacks and chronic pain. In pediatric patients it is relatively frequently used to treat pavor nocturnus and nocturnal enuresis.
Mechanism of Action
Imipramine, a tertiary amine, inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. More on [ Imipramine ]
Antidepressants :: Drugs and Medications
Amitriptyline (Elavil, Endep) Clomipramine (Anafranil) Doxepin (Adapin, Sinequan) Imipramine (Tofranil) Trimipramine (Surmontil)
Elchupenibre79 (Casper Lombago) Mon, 02 Nov 2009 23:54:03 -0000
Amitriptyline (Elavil, Endep) Clomipramine (Anafranil) Doxepin (Adapin, Sinequan) Imipramine (Tofranil) Trimipramine (Surmontil)
RT WOW *makinkagum @novariyanti: Mengangguk2. RT @digma_epiphanic: Nih authornya mahadewa, mahadewi, imipramine, ama 30hr mncari cinta bkn?
PHREDZ (Frederick Gaghauna) Sun, 01 Nov 2009 02:03:52 -0000
RT WOW *makinkagum @novariyanti: Mengangguk2. RT @digma_epiphanic: Nih authornya mahadewa, mahadewi, imipramine, ama 30hr mncari cinta bkn?
Mengangguk-angguk. RT @digma_epiphanic: Nih @novariyanti authornya mahadewa, mahadewi, imipramine, ama 30hr mncari cinta bkn?
novariyanti (dr.NoRiYu,SpKJ) Sun, 01 Nov 2009 01:55:56 -0000
Mengangguk-angguk. RT @digma_epiphanic: Nih @novariyanti authornya mahadewa, mahadewi, imipramine, ama 30hr mncari cinta bkn?
Antidepressants: Imipramine and Tricyclic Antidepressants http://bit.ly/1oQuoL
vitarleton (Vicataria Tarleton) Fri, 30 Oct 2009 20:53:56 -0000
Antidepressants: Imipramine and Tricyclic Antidepressants http://bit.ly/1oQuoL
A case of imipramine-associated immune thrombocytopenia. - http://bit.ly/2dLPsz
ALLeukemiaChild (ALL Leukemia CHild) Fri, 30 Oct 2009 08:07:59 -0000
A case of imipramine-associated immune thrombocytopenia. - http://bit.ly/2dLPsz
DrugDigest: Imipramine ( Tofranil ) - Information on dosage, usage, side effects, interactions, and drug comparisons including generics when available.
Imipramine - Drug monograph from Internet Mental Health includes pharmacology, indications, contraindications, precautions, adverse effects, dosage and research.
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